5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione

Base Information

• Chemical Name: 5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione
• CAS No.: 142484-26-2
• Molecular Formula: C₇H₉NO₄
• Molecular Weight: 171.153
• Mol file: 142484-26-2.mol

Synonyms:5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione

Chemical Property of 5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione

There total 1 articles about 5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-oxazolidinedione (2346-26-1) + 3-chloro-2-butanone (4091-39-8) → 5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione (142484-26-2) + 5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione (142484-27-3)

Guidance literature:

With tert.-butyl lithium; lithium chloride; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1) THF, pentane, -78 deg C, 30 min, 2) THF, pentane, a) -78 deg C, 10 min, b) 25 deg C, 5 h;

DOI:10.1021/jo00042a045

Reference yield: 63.0%

5-(2-hydroxy-1-methylpropylidene)-2,4-oxazolidinedione (142484-26-2) → sotolone (28664-35-9)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 3.5h;

DOI:10.1021/jo00042a045

upstream raw materials:

2,4-oxazolidinedione

3-chloro-2-butanone

Downstream raw materials:

sotolone

Refernces