N-pyrimidin-2-ylglycine

Base Information

• Chemical Name: N-pyrimidin-2-ylglycine
• CAS No.: 79858-46-1
• Molecular Formula: C6H7 N3 O2
• Molecular Weight: 153.13868
• European Community (EC) Number: 833-385-6
• DSSTox Substance ID: DTXSID60585505
• Nikkaji Number: J2.270.024C
• Wikidata: Q82477481
• Mol file: 79858-46-1.mol

Synonyms:79858-46-1;N-pyrimidin-2-ylglycine;2-(pyrimidin-2-ylamino)acetic acid;(pyrimidin-2-ylamino)acetic acid;2-[(pyrimidin-2-yl)amino]acetic acid;MFCD03007289;Glycine,N-2-pyrimidinyl-;SCHEMBL2401111;N-2-PYRIMIDINYL-GLYCINE;DTXSID60585505;Glycine,N-2-pyrimidinyl-(9CI);2-(pyrimidin-2-ylamino)aceticacid;AKOS000203152;AB12962;VS-02756;2-(2-PYRIMIDINYLAMINO)ACETIC ACID;CS-0245578;EN300-30699;F78917;Z228588498

Chemical Property of N-pyrimidin-2-ylglycine

Chemical Property:

• PSA: 75.11000
• LogP: 0.04610
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 153.053826475
• Heavy Atom Count: 11
• Complexity: 134

Purity/Quality:

98%min ^*data from raw suppliers

N-2-Pyrimidinyl-glycine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(N=C1)NCC(=O)O

Technology Process of N-pyrimidin-2-ylglycine

There total 3 articles about N-pyrimidin-2-ylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-chloropyrimidine (1722-12-9,1195939-87-7) + BOC-glycine (4530-20-5) → N-(pyrimidin-2-yl)glycine (79858-46-1)

Guidance literature:

Multistep reaction;

DOI:10.3390/80600467

Reference yield:

C7H9N3O2 (1042503-63-8) → N-(pyrimidin-2-yl)glycine (79858-46-1)

Guidance literature:

With hydrogenchloride; In methanol; water; at 60 ℃;

DOI:10.1134/S107036321012025X

Reference yield:

→ N-(pyrimidin-2-yl)glycine (79858-46-1)

Guidance literature:

upstream raw materials:

2-chloropyrimidine

BOC-glycine

C₇H₉N₃O₂

Refernces

• 1、 Babaev,Ermolat'ev. "Basic techniques of working on a solid phase: From ABC of the peptide synthesis to libraries of non-natural amino acids". experimental part. p. 2572 - 2589. Retrieved 2011/04/15.