2-Dimethoxyethoxybenzaldehyde

Base Information

• Chemical Name: 2-Dimethoxyethoxybenzaldehyde
• CAS No.: 74401-08-4
• Molecular Formula: C11H14 O4
• Molecular Weight: 210.23
• Mol file: 74401-08-4.mol

Synonyms:2-Dimethoxyethoxybenzaldehyde;2-Dimethoxyethoxybenzaldehyde, GC 97%

Chemical Property of 2-Dimethoxyethoxybenzaldehyde

Chemical Property:

• PSA: 44.76000
• LogP: 1.49680

Purity/Quality:

98%Min ^*data from raw suppliers

2-DIMETHOXYETHOXYBENZALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Dimethoxyethoxybenzaldehyde

There total 5 articles about 2-Dimethoxyethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1-bromo-2,2-dimethoxyethane (7252-83-7) + salicylaldehyde (90-02-8) → 2-(2,2-dimethoxyethoxy)benzaldehyde (74401-08-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃;

DOI:10.1002/adsc.201801225

Reference yield: 46.6%

chloroacetaldehyde dimethyl acetal (97-97-2) + salicylaldehyde (90-02-8) → 2-(2,2-dimethoxyethoxy)benzaldehyde (74401-08-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 140 ℃; for 2h;

Reference yield: 30.0%

1-bromo-2,2-dimethoxyethane (7252-83-7) + sodium salicylate (3116-83-4) → 2-(2,2-dimethoxyethoxy)benzaldehyde (74401-08-4)

Guidance literature:

In N,N-dimethyl-formamide; at 70 ℃; for 48h;

upstream raw materials:

chloroacetaldehyde dimethyl acetal

salicylaldehyde

Bromoacetaldehyde diethyl acetal

1-bromo-2,2-dimethoxyethane

Downstream raw materials:

benzofuran-2-yl-methanol

benzofuran-2-ylmethanamine

C₂₄H₂₃NO₆

(4-Benzofuran-2-yl-4,5-dihydro-3H-pyrrol-2-yl)-phenethyl-amine

Refernces

• 1、 Phillips, Eric M.,Wadamoto, Manabu,Roth, Howard S.,Ott, Andrew W.,Scheidt, Karl A.. "Nhc-catalyzed reactions of aryloxyacetaldehydes: A domino elimination/conjugate addition/acylation process for the synthesis of substituted coumarins". supporting information; experimental part. p. 105 - 108. Retrieved 2009/06/28.
• 2、 Langhals, Heinz,Pust, Stefan. "Fluorescent Dyes with Large Stokes Shifts - a Simple Synthesis of -3,3'-diol". . p. 4674 - 4681. Retrieved 2007/10/02.