2-(Methoxymethoxy)-1-[2-(methoxymethoxy)naphthalen-1-yl]naphthalene

Base Information

• Chemical Name: 2-(Methoxymethoxy)-1-[2-(methoxymethoxy)naphthalen-1-yl]naphthalene
• CAS No.: 74292-20-9
• Molecular Formula: C₂₄H₂₂O₄
• Molecular Weight: 374.436
• Hs Code.: 2909309090
• European Community (EC) Number: 633-997-1,634-273-8,804-314-6
• Nikkaji Number: J1.188.401F,J3.322.872D
• Mol file: 74292-20-9.mol

Synonyms:173831-50-0;142128-92-5;(R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene;(S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene;74292-20-9;(R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl;2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHALENE;2-(methoxymethoxy)-1-[2-(methoxymethoxy)naphthalen-1-yl]naphthalene;(R)-(+)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl;1,1'-Binaphthalene, 2,2'-bis(methoxymethoxy)-;(S)-(-)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;1,1'-Binaphthalene, 2,2'-bis(methoxymethoxy)-, (1R)-;(S)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHALENE;(R)-(+)-2,2/'-BIS(METHOXYMETHOXY)-1,1/'-BINAPHTHYL;(R)-2,2/'-Bis(methoxymethoxy)-1,1/'-binaphthalene;SCHEMBL1446528;AC9224;AKOS015911249;CS-W011783;SC11849;1,1'-Bi[2-(methoxymethoxy)naphthalene];DS-14105;SY009989;SY009990;B3202;B3203;CS-0031335;FT-0663336;C73331;10.14272/YIAQRNNJNMLGTP-UHFFFAOYSA-N.1;A885237;(aR)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene;doi:10.14272/YIAQRNNJNMLGTP-UHFFFAOYSA-N.1;J-010946;2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene, 97%;(R)-(+)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene, 97%;(S)-(-)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene, 97%;(S)-(-)-2,2?-BIS(METHOXYMETHOXY)-1,1?-BINAPHTHALENE;(R)-(+)-2,2 inverted exclamation mark -Bis(methoxymethoxy)-1,1 inverted exclamation mark -binaphthalene;(S)-(-)-2,2 inverted exclamation mark -Bis(methoxymethoxy)-1,1 inverted exclamation mark -binaphthalene

Chemical Property of 2-(Methoxymethoxy)-1-[2-(methoxymethoxy)naphthalen-1-yl]naphthalene

Chemical Property:

• Melting Point: 92-96 °C(lit.)
• Boiling Point: 477.8±45.0 °C(Predicted)
• PSA: 36.92000
• Density: 1.182±0.06 g/cm3(Predicted)
• LogP: 5.62540
• XLogP3: 5.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 374.15180918
• Heavy Atom Count: 28
• Complexity: 428

Purity/Quality:

2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,N
• Statements: 41-50/53
• Safety Statements: 26-39-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCOC1=C(C2=CC=CC=C2C=C1)C3=C(C=CC4=CC=CC=C43)OCOC

Technology Process of 2-(Methoxymethoxy)-1-[2-(methoxymethoxy)naphthalen-1-yl]naphthalene

There total 8 articles about 2-(Methoxymethoxy)-1-[2-(methoxymethoxy)naphthalen-1-yl]naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(S)-[1,1']-binaphthalenyl-2,2'-diol (18531-99-2) + chloromethyl methyl ether (107-30-2) → (S)-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl (74292-20-9,142128-92-5)

Guidance literature:

With sodium hydride; In tetrahydrofuran;

DOI:10.1021/ja021244h

Reference yield: 98.0%

(R)-binaphthol (602-09-5,18531-99-2,18531-94-7) + chloromethyl methyl ether (107-30-2) → (R,R)-2,2'-bis(methoxymethoxy)-1,1'-binaphthol (142128-92-5,173831-50-0,74292-20-9)

Guidance literature:

(R)-binaphthol; With sodium hydride; In tetrahydrofuran; at 0 - 10 ℃; for 1h;

chloromethyl methyl ether; In tetrahydrofuran; at 0 - 10 ℃;

Reference yield: 84.0%

Dimethoxymethane (109-87-5) + (S)-[1,1']-binaphthalenyl-2,2'-diol (18531-99-2) → (S)-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl (74292-20-9,142128-92-5)

Guidance literature:

With phosphorus pentoxide; In dichloromethane;

DOI:10.1021/jo9018446

upstream raw materials:

Iodomethyl methyl ether

(S)-[1,1']-binaphthalenyl-2,2'-diol

chloromethyl methyl ether

Dimethoxymethane

Downstream raw materials:

3,3’-dimethyl-[1,1’-binaphthalene]-2,2’-diol

3,3'-bis(1-(p-bromophenyl)-1H-1,2,3-triazol-4-yl)-1,1'-binaphthyl-2,2'-diyl N-(p-bromophenyl)(1-pyrrolidinyl)phosphonimidate

(S)-2,2’-bis(methoxymethoxy)-3,3’-diiodo-1,1’-binaphthalene

(S)-3,3’-dibromo-2,2’-bis(methoxymethoxy)-1,1’-binaphthalene

Refernces

• 1、 Hong, Tao,Zhang, Zibin,Sun, Yan,Tao, Jia-Ju,Tang, Jia-Dong,Xie, Chunsong,Wang, Min,Chen, Fang,Xie, Shang-Shu,Li, Shijun,Stang, Peter J.. "Chiral Metallacycles as Catalysts for Asymmetric Conjugate Addition of Styrylboronic Acids to α,β-Enones". supporting information. p. 10244 - 10249. Retrieved 2020/09/21.
• 2、 -. "PROCESS FOR POLYMERIZING BETA-BUTYROLACTONE". Paragraph 0120; 0124; 0125-0129; 0130-0132. . Retrieved 2020/12/03.