4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester

Base Information

• Chemical Name: 4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester
• CAS No.: 16034-06-3
• Molecular Formula: C₂₀H₁₄O₅
• Molecular Weight: 334.328
• Mol file: 16034-06-3.mol

Synonyms:4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester

Chemical Property of 4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester

There total 1 articles about 4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.3%

4-hydroxyisophthalic acid (636-46-4) + phenol (108-95-2,27073-41-2) → 4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester (16034-06-3)

Guidance literature:

With thionyl chloride; for 1h; Cooling with ice; Reflux;

Reference yield: 86.0%

1-bromo-octane (111-83-1) + 4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester (16034-06-3) → phenyl 4-hydroxy-3-nonanoylbenzoate

Guidance literature:

With 1,10-Phenanthroline; nickel(II) bromide diethylene glycol dimethyl ether; zinc; In N,N-dimethyl-formamide; at 60 ℃; for 10h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.0c03342

Reference yield: 71.0%

4-hydroxy-1,3-benzenedicarboxylic acid diphenyl ester (16034-06-3) + (6-bromohexyloxy)-tert-butyldimethylsilane (129368-70-3) → phenyl 3-(7-((tert-butyldimethylsilyl)oxy)heptanoyl)-4-hydroxybenzoate

Guidance literature:

With 1,10-Phenanthroline; nickel(II) bromide diethylene glycol dimethyl ether; zinc; In N,N-dimethyl-formamide; at 60 ℃; for 10h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.0c03342

upstream raw materials:

4-hydroxyisophthalic acid

phenol

Refernces

• 1、 -. "4-Hydroxyl-1,3 di-phthalate derivatives and preparation and application thereof". Paragraph 0045; 0046. . Retrieved 2017/01/02.