triphenylacetic acid anilide

Base Information

• Chemical Name: triphenylacetic acid anilide
• CAS No.: 28716-48-5
• Molecular Formula: C₂₆H₂₁NO
• Molecular Weight: 363.459
• Mol file: 28716-48-5.mol

Synonyms:triphenylacetic acid anilide

Chemical Property of triphenylacetic acid anilide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of triphenylacetic acid anilide

There total 6 articles about triphenylacetic acid anilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

triphenylacetyl chloride (6068-70-8) + aniline (62-53-3) → triphenylacetic acid anilide (28716-48-5)

Guidance literature:

With dmap; triethylamine; In dichloromethane; for 48h;

DOI:10.1021/ja042913p

Reference yield: 90.0%

triphenylacetic acid (595-91-5) + N-tert-butyl-N'-phenyl-S-phenylisothiourea → triphenylacetic acid anilide (28716-48-5)

Guidance literature:

With iron(III)-acetylacetonate; In iso-butanol; at 98 ℃; for 24h; Microwave irradiation;

DOI:10.1021/acs.orglett.6b02247

Reference yield: 44.0%

triphenylacetic acid (595-91-5) + aniline (62-53-3) → triphenylacetic acid anilide (28716-48-5)

Guidance literature:

triphenylacetic acid; With 2,4,4,6-Tetrabromo-2,5-cyclohexadien-1-one; triphenylphosphine; In dichloromethane; at 0 - 10 ℃; for 1h;

aniline; In dichloromethane;

DOI:10.1007/s11178-005-0042-0

upstream raw materials:

tetraphenyl-acetimidoyl chloride

triphenylacetyl chloride

aniline

triphenylacetic acid

Downstream raw materials:

tetraphenyl-acetimidoyl chloride

Refernces

• 1、 Zhu, Yan-Ping,Sergeyev, Sergey,Franck, Philippe,Orru, Romano V. A.,Maes, Bert U. W.. "Amine Activation: Synthesis of N-(Hetero)arylamides from Isothioureas and Carboxylic Acids". supporting information. p. 4602 - 4605. Retrieved 2016/09/28.