4-CHLORO-3-HYDROXY 1H-INDAZOLE

Base Information

• Chemical Name: 4-CHLORO-3-HYDROXY 1H-INDAZOLE
• CAS No.: 787580-87-4
• Molecular Formula: C₇H₅ClN₂O
• Molecular Weight: 168.583
• Hs Code.: 2933990090
• Mol file: 787580-87-4.mol

Synonyms:4-CHLORO-3-HYDROXY 1H-INDAZOLE;4-chloro-1,2-dihydro-3H-Indazol-3-one

Chemical Property of 4-CHLORO-3-HYDROXY 1H-INDAZOLE

Chemical Property:

• Vapor Pressure: 0.027mmHg at 25°C
• Refractive Index: 1.604
• Boiling Point: 246.446°C at 760 mmHg
• PKA: 11.01±0.20(Predicted)
• Flash Point: 102.847°C
• PSA: 48.91000
• Density: 1.416g/cm³
• LogP: 1.92190
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-1,2-dihydro-3H-indazol-3-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLORO-3-HYDROXY 1H-INDAZOLE

There total 3 articles about 4-CHLORO-3-HYDROXY 1H-INDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-6-hydrazino-benzoic acid (855471-41-9) → 4-chloro-1,2-dihydro-indazol-3-one (787580-87-4)

Guidance literature:

With water;

Reference yield:

2-chloro-6-aminobenzoic acid (2148-56-3) → 4-chloro-1,2-dihydro-indazol-3-one (787580-87-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfur dioxide; water / anschliessend Behandeln mit wss. Salzsaeure

2: H₂O

With sulfur dioxide; water;

Reference yield:

2-chloro-6-hydrazino-benzoic acid (855471-41-9) + benzaldehyde (100-52-7) → 4-chloro-1,2-dihydro-indazol-3-one (787580-87-4) + 5-chloro-3-phenyl-1H-cinnolin-4-one

Guidance literature:

upstream raw materials:

2-chloro-6-hydrazino-benzoic acid

benzaldehyde

2-chloro-6-aminobenzoic acid