Technology Process of (Z)-4-benzylidene-6-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one
There total 3 articles about (Z)-4-benzylidene-6-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1,4-diaza-bicyclo[2.2.2]octane; silver(I) acetate;
In
dimethyl sulfoxide;
at 20 ℃;
for 24h;
under 7500.75 Torr;
Autoclave;
DOI:10.1021/ol303534w
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere
2: silver(I) acetate; 1,4-diaza-bicyclo[2.2.2]octane / dimethyl sulfoxide / 24 h / 20 °C / 7500.75 Torr / Autoclave
With
1,4-diaza-bicyclo[2.2.2]octane; copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; silver(I) acetate; triethylamine;
In
tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/ol303534w
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iodine; sodium hydrogencarbonate / water / 8 h / 0 °C
2: copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere
3: silver(I) acetate; 1,4-diaza-bicyclo[2.2.2]octane / dimethyl sulfoxide / 24 h / 20 °C / 7500.75 Torr / Autoclave
With
1,4-diaza-bicyclo[2.2.2]octane; copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; iodine; silver(I) acetate; sodium hydrogencarbonate; triethylamine;
In
tetrahydrofuran; water; dimethyl sulfoxide;
DOI:10.1021/ol303534w