Technology Process of C38H34N2
There total 8 articles about C38H34N2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
zinc(II) chloride;
In
toluene;
at 25 - 120 ℃;
for 0.666667h;
optical yield given as %de;
enantioselective reaction;
Inert atmosphere;
DOI:10.1021/ol300717e
- Guidance literature:
-
Multi-step reaction with 5 steps
1: (1S)-(+)-10-camphorsulfonic acid / dichloromethane / 24 h / 25 °C
2: dichloromethane / 6 h / -10 - 20 °C / Inert atmosphere
3: potassium carbonate; potassium iodide / acetonitrile / 12 h / Reflux
4: trifluoroacetic acid / dichloromethane / 6.25 h / -10 - 20 °C / Inert atmosphere
5: zinc(II) chloride / toluene / 0.67 h / 25 - 120 °C / Inert atmosphere
With
(1S)-(+)-10-camphorsulfonic acid; potassium carbonate; trifluoroacetic acid; potassium iodide; zinc(II) chloride;
In
dichloromethane; toluene; acetonitrile;
DOI:10.1021/ol300717e
- Guidance literature:
-
Multi-step reaction with 6 steps
1: titanium(IV) isopropylate; zinc / dichloromethane / 1 h / 0 °C / Inert atmosphere
2: (1S)-(+)-10-camphorsulfonic acid / dichloromethane / 24 h / 25 °C
3: dichloromethane / 6 h / -10 - 20 °C / Inert atmosphere
4: potassium carbonate; potassium iodide / acetonitrile / 12 h / Reflux
5: trifluoroacetic acid / dichloromethane / 6.25 h / -10 - 20 °C / Inert atmosphere
6: zinc(II) chloride / toluene / 0.67 h / 25 - 120 °C / Inert atmosphere
With
(1S)-(+)-10-camphorsulfonic acid; titanium(IV) isopropylate; potassium carbonate; trifluoroacetic acid; potassium iodide; zinc(II) chloride; zinc;
In
dichloromethane; toluene; acetonitrile;
DOI:10.1021/ol300717e
