Bis(benzoylmethyl) sulfide

Base Information

• Chemical Name: Bis(benzoylmethyl) sulfide
• CAS No.: 2461-80-5
• Molecular Formula: C16H14O2S
• Molecular Weight: 270.352
• Hs Code.: 2930909090
• Mol file: 2461-80-5.mol

Synonyms:Acetophenone,2,2''-thiodi- (7CI,8CI);2,2''-Thiodiacetophenone;Bis(2-oxo-2-phenylethyl)sulfide;Ethanone,2,2'-thiobis[1-phenyl-;Diphenacyl sulfide;NSC 68428;2-(2-Oxo-2-phenyl-ethylsulfanyl)-1-phenyl-ethanone;2,2'-Sulfanediylbis(1-phenylethanone);Thiodiacetophenone;1,1'-Diphenyl-2,2'-sulfanediyl-bis-ethanone;

Chemical Property of Bis(benzoylmethyl) sulfide

Chemical Property:

• Melting Point: 77 °C
• Boiling Point: 434.5 °C at 760 mmHg
• Flash Point: 188.8 °C
• PSA: 59.44000
• Density: 1.189 g/cm³
• LogP: 3.48540

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bis(benzoylmethyl) Sulfide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bis(benzoylmethyl) sulfide

There total 21 articles about Bis(benzoylmethyl) sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-mercaptoacetophenone (2462-02-4) + α-bromoacetophenone (70-11-1) → diphenacyl sulfide (2461-80-5)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1002/ejoc.202001343

Reference yield: 98.0%

α-bromoacetophenone (70-11-1) → diphenacyl sulfide (2461-80-5)

Guidance literature:

With bis(tributyltin)sulfide; cesium fluoride; In ethyl acetate; N,N-dimethyl-formamide; at 20 ℃; for 1h; with TBAF*3H₂O, too;

DOI:10.1016/S0040-4039(00)96513-4

Reference yield:

2-phenacylthioimidazoline (32188-99-1) → imidazolidone (120-93-4) + N,N'-ethylenethiourea (96-45-7) + diphenacyl sulfide (2461-80-5)

Guidance literature:

With water; for 1h; Heating;

upstream raw materials:

thiophenol

α-bromoacetophenone

1-chloroacetophenone

2-methylthio-1-phenyl-ethanone

Downstream raw materials:

3,5-Diphenyl-2H-1,4-thiazine

Diphenacyl sulfone

2,7-dihydro-3,6-diphenyl-1,4,5-thiadiazepine

bis(benzoylmethyl) sulfoxide

Refernces

• 1、 Gao, Han,Connors, David M.,Goroff, Nancy S.. "Synthesis of Phenanthro[9,10-c]thiophenes by 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-Promoted Cyclo-Oxidation". . p. 630 - 633. Retrieved 2019/05/21.
• 2、 Eller, Christina,Kehr, Gerald,Daniliuc, Constantin G.,Stephan, Douglas W.,Erker, Gerhard. "Thiophene synthesis via 1,1-carboboration". supporting information. p. 7226 - 7229. Retrieved 2015/04/27.