3-Pyridinesulfonamide,4-hydrazino-(9CI)

Base Information

• Chemical Name: 3-Pyridinesulfonamide,4-hydrazino-(9CI)
• CAS No.: 73742-76-4
• Molecular Formula: C5H8 N4 O2 S
• Molecular Weight: 188.21
• Hs Code.: 29349990
• Mol file: 73742-76-4.mol

Synonyms:3-Pyridinesulfonamide,4-hydrazino- (9CI); 4-Hydrazino-3-pyridinesulfonamide

Chemical Property of 3-Pyridinesulfonamide,4-hydrazino-(9CI)

Chemical Property:

• PSA: 122.71000
• LogP: 0.91790

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Hydrazinylpyridine-3-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinesulfonamide,4-hydrazino-(9CI)

There total 1 articles about 3-Pyridinesulfonamide,4-hydrazino-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-chloropyridine-3-sulphonamide (33263-43-3) → 4-hydrazinyl-3-pyridinesulfonamide (73742-76-4)

Guidance literature:

With hydrazine hydrate; In methanol; at 20 ℃; for 20h; Reflux;

DOI:10.1016/j.ejmech.2010.02.020

Reference yield:

4-hydrazinyl-3-pyridinesulfonamide (73742-76-4) → N-(phenylcarbamoyl)-4-(3,4,5-trimethyl-1H-pyrazol-1-yl)-3-pyridinesulfonamide

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid / 2 h / Reflux

2: potassium carbonate / acetone / 24 h / 20 °C

3: hydrogenchloride / water / 16 h / 20 °C / pH 2

With hydrogenchloride; potassium carbonate; acetic acid; In water; acetone;

DOI:10.3390/molecules200712029

Reference yield:

4-hydrazinyl-3-pyridinesulfonamide (73742-76-4) → N-[(4-chlorophenyl)carbamoyl]-4-(3,4,5-trimethyl-1H-pyrazol-1-yl)-3-pyridinesulfonamide

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid / 2 h / Reflux

2: potassium carbonate / acetone / 24 h / 20 °C

3: hydrogenchloride / water / 16 h / 20 °C / pH 2

With hydrogenchloride; potassium carbonate; acetic acid; In water; acetone;

DOI:10.3390/molecules200712029

upstream raw materials:

4-chloropyridine-3-sulphonamide

Refernces

• 1、 Szafrański, Krzysztof,S?awiński, Jaros?aw,K?dzia, Anna,Kwapisz, Ewa. "Syntheses of novel 4-substituted N-(5-amino-1H-1,2,4-triazol-3-yl)pyridine-3-sulfonamide derivatives with potential antifungal activity". . . Retrieved 2017.