(S)-Benzyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate

Base Information Edit

Chemical Name:(S)-Benzyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate
CAS No.:73724-46-6
Molecular Formula:C25H23 N O5
Molecular Weight:417.45
Hs Code.:
DSSTox Substance ID:DTXSID101173017
Nikkaji Number:J1.399.075A
Mol file:73724-46-6.mol

Synonyms:73724-46-6;Fmoc-Ser-Obzl;(S)-Benzyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate;FMOC-L-SER-OBZL;benzyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate;Fmoc-L-serine benzyl ester;SCHEMBL13402442;DTXSID101173017;L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl ester;L-Serine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl ester;MFCD09752867;AKOS015924460;CS-W022731;DS-3694;HY-W041991;I11515;EN300-7414310;N-(9-fluorenylmethoxycarbonyl)-l-serine benzyl ester;N-(9H-Fluorene-9-ylmethoxycarbonyl)-L-serine benzyl ester;N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-serine benzyl ester;N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-SERINE PHENYLMETHYL ESTER;benzyl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxypropanoate

Suppliers and Price of (S)-Benzyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Fmoc-L-Ser-Obzl
100mg
$ 75.00

Chem-Impex
Fmoc-L-serinebenzylester,99%(HPLC) 99%(HPLC)
5G
$ 58.52

Chem-Impex
Fmoc-L-serinebenzylester,≥99%(HPLC) ≥99%(HPLC)
25G
$ 215.78

Ark Pharm
Fmoc-Ser-Obzl 98%
5g
$ 18.00

American Custom Chemicals Corporation
FMOC-L-SER-OBZL 95.00%
5MG
$ 495.67

American Custom Chemicals Corporation
FMOC-L-SER-OBZL 95.00%
1G
$ 1575.00

AK Scientific
(S)-Benzyl2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate
250mg
$ 69.00

AK Scientific
(S)-Benzyl2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate
25g
$ 250.00

Activate Scientific
Fmoc-L-serine benzyl ester 98%
5 g
$ 86.00

Activate Scientific
Fmoc-L-serine benzyl ester 98%
25 g
$ 257.00

Total 30 raw suppliers

Chemical Property of (S)-Benzyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:98-100℃
Refractive Index:1.621
Boiling Point:656.217°C at 760 mmHg
PKA:10.05±0.46(Predicted)
Flash Point:350.667°C
PSA：84.86000
Density:1.279g/cm³
LogP:4.58600
Storage Temp.:2-8°C
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:417.15762283
Heavy Atom Count:31
Complexity:583

Purity/Quality:

99% ^*data from raw suppliers

Fmoc-L-Ser-Obzl ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)C(CO)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)[C@H](CO)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Uses Fmoc-L-Ser-Obzl is used as a reactant in the solid-phase synthesis of peptides.

Technology Process of (S)-Benzyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate

There total 9 articles about (S)-Benzyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 100-39-0
benzyl bromide

: 73724-45-5
N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine

: 118358-66-0,73724-46-6
N-(9-fluorenylmethyloxycarbonyl)-L-serine benzyl ester

Guidance literature:: N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine; With caesium carbonate; In tetrahydrofuran; water; at 20 ℃; for 0.5h;

benzyl bromide; In N,N-dimethyl-formamide; for 3h;
DOI:10.1016/j.carres.2021.108495