3-chloro-5-(trifluoromethyl)-2-pyridinyl tosylate

Base Information

• Chemical Name: 3-chloro-5-(trifluoromethyl)-2-pyridinyl tosylate
• CAS No.: 1174281-15-2
• Molecular Formula: C₁₃H₉ClF₃NO₃S
• Molecular Weight: 351.734
• Mol file: 1174281-15-2.mol

Synonyms:3-chloro-5-(trifluoromethyl)-2-pyridinyl tosylate

Chemical Property of 3-chloro-5-(trifluoromethyl)-2-pyridinyl tosylate

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of 3-chloro-5-(trifluoromethyl)-2-pyridinyl tosylate

There total 1 articles about 3-chloro-5-(trifluoromethyl)-2-pyridinyl tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

3-chloro-5-(trifluoromethyl)-2-hydroxypyridine (76041-71-9) + p-toluenesulfonyl chloride (98-59-9) → 3-chloro-5-(trifluoromethyl)-2-pyridinyl tosylate (1174281-15-2)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1002/chem.200900313

upstream raw materials:

3-chloro-5-(trifluoromethyl)-2-hydroxypyridine

p-toluenesulfonyl chloride

Refernces