3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole

Base Information

• Chemical Name: 3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole
• CAS No.: 118657-91-3
• Molecular Formula: C₁₈H₁₃ClN₂O₂
• Molecular Weight: 324.766
• Mol file: 118657-91-3.mol

Synonyms:3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole

Chemical Property of 3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole

There total 1 articles about 3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

(1-diazoethyl)benzene (22293-10-3) + 2-chloro-1,4-naphthoquinone (1010-60-2) → 1a,7a-dihydro-1a-chloro-endo-1-methyl-exo-1-phenyl-1H-cyclopropanaphthalene-2,7-dione (118657-92-4,118758-19-3) + 3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole (118657-91-3)

Guidance literature:

In diethyl ether; at 0 ℃; for 1h;

DOI:10.1021/jo00266a027

Reference yield: 91.0%

3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole (118657-91-3) → 1a,7a-dihydro-1a-chloro-endo-1-methyl-exo-1-phenyl-1H-cyclopropanaphthalene-2,7-dione (118657-92-4,118758-19-3) + 1a,7a-dihydro-1a-chloro-1-methyl-endo-1-phenyl-1H-cyclopropanaphthalene-2,7-dione (118657-92-4,118758-19-3)

Guidance literature:

In benzene; for 9h; Heating;

DOI:10.1021/jo00266a027

Reference yield: 90.0%

3a,4,9,9a-tetrahydro-9a-chloro-exo-3-methyl-endo-3-phenyl-4,9-dioxo-3H-benzindazole (118657-91-3) → 4,9-dihydro-3-methyl-3-phenyl-4,9-dioxo-3H-benzindazole (123700-58-3)

Guidance literature:

With triethylamine; In dichloromethane; for 48h; Ambient temperature;

DOI:10.1021/jo00286a022

upstream raw materials:

(1-diazoethyl)benzene

2-chloro-1,4-naphthoquinone

Downstream raw materials:

4,9-dihydro-3-methyl-3-phenyl-4,9-dioxo-3H-benzindazole

1a,7a-dihydro-1a-chloro-endo-1-methyl-exo-1-phenyl-1H-cyclopropanaphthalene-2,7-dione

1a,7a-dihydro-1a-chloro-1-methyl-endo-1-phenyl-1H-cyclopropanaphthalene-2,7-dione

Refernces