4-Chloro-3-methylphenyl Hydrogen Succinate

Base Information

• Chemical Name: 4-Chloro-3-methylphenyl Hydrogen Succinate
• CAS No.: 127275-12-1
• Molecular Formula: C₁₁H₁₁ClO₄
• Molecular Weight: 242.659
• Mol file: 127275-12-1.mol

Synonyms:4-Chloro-3-methylphenyl Hydrogen Succinate

Chemical Property of 4-Chloro-3-methylphenyl Hydrogen Succinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Chloro-3-methylphenyl Hydrogen Succinate

There total 1 articles about 4-Chloro-3-methylphenyl Hydrogen Succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

succinic acid anhydride (108-30-5) + 4-Chloro-3-methylphenol (59-50-7) → 4-Chloro-3-methylphenyl Hydrogen Succinate (127275-12-1)

Guidance literature:

With sodium hydroxide; In water; for 0.166667h; Ambient temperature;

DOI:10.1007/BF00811125

Reference yield: 7.0%

4-Chloro-3-methylphenyl Hydrogen Succinate (127275-12-1) → 4-Chloro-3-methylphenol (59-50-7) + 4-(2-Hydroxy-4-methylphenyl)-4-oxobutanoic Acid (59010-46-7) + 4-(5-Chloro-2-hydroxy-4-methylphenyl)-4-oxobutanoic Acid (62903-21-3)

Guidance literature:

In ethanol; for 20h; Ambient temperature; Irradiation;

DOI:10.1007/BF00811125

Reference yield:

methanol (67-56-1) + 4-Chloro-3-methylphenyl Hydrogen Succinate (127275-12-1) → 4-Chloro-3-methylphenol (59-50-7) + Methyl 4-(2-Hydroxy-4-methylphenyl)-4-oxobutanoate (59010-47-8) + Methyl 4-(5-Chloro-2-hydroxy-4-methylphenyl)-4-oxobutanoate (127275-14-3)

Guidance literature:

With sulfuric acid; Multistep reaction; 1.) ethanol, irradiation, 20 h, RT; 2.) 4 h, reflux;

DOI:10.1007/BF00811125

upstream raw materials:

succinic acid anhydride

4-Chloro-3-methylphenol

Downstream raw materials:

4-Chloro-3-methylphenol

Methyl 4-(2-Hydroxy-4-methylphenyl)-4-oxobutanoate

Methyl 4-(5-Chloro-2-hydroxy-4-methylphenyl)-4-oxobutanoate

4-(2-Hydroxy-4-methylphenyl)-4-oxobutanoic Acid

Refernces