(S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate

Base Information

• Chemical Name: (S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate
• CAS No.: 28078-91-3
• Molecular Formula: C₁₃H₅F₅OS
• Molecular Weight: 304.24
• Mol file: 28078-91-3.mol

Synonyms:(S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate

Chemical Property of (S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate

There total 9 articles about (S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

bis(pentafluorophenyl) disulfide (1494-06-0) + benzaldehyde (100-52-7) → (S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate (28078-91-3)

Guidance literature:

With cetyltrimethylammonim bromide; 2,2’-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride; In water; at 50 ℃; for 24h;

DOI:10.1002/chem.200400754

Reference yield: 33.0%

pentafluorophenylthiol (771-62-0) + tert-butyl benzoyl(tert-butoxycarbonyl)carbamate (135364-97-5) → (S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate (28078-91-3)

Guidance literature:

With sodium carbonate; In 1,4-dioxane; at 80 ℃; for 18h; Inert atmosphere;

DOI:10.1177/1747519819873514

Reference yield:

pentafluorophenylthiol (771-62-0) + α,α,α-trifluorotoluene (98-08-8) → (S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate (28078-91-3) + C19H5ClF10S2 (137730-97-3)

Guidance literature:

With aluminium trichloride; In chloroform; at 60 - 70 ℃; for 6h;

DOI:10.1016/S0022-1139(99)00080-9

upstream raw materials:

lead pentafluorothiophenolate

benzoyl chloride

pentafluorophenylthiol

α,α,α-trifluorotoluene

Refernces

• 1、 Nambu, Hisanori,Hata, Kayoko,Matsugi, Masato,Kita, Yasuyuki. "Efficient synthesis of thioesters and amides from aldehydes by using an intermolecular radical reaction in water". . p. 719 - 727. Retrieved 2007/10/03.
• 2、 Petrova,Platonov,Maksimov. "Fluoro-organic sulphur-containing compounds. IV. Haloalkylation reactions of polyfluorinated thiophenols with CHal3R compounds in the presence of AlCl3: Synthesis and some reactions of polyfluorophenylthio derivatives of halomethanes". . p. 17 - 28. Retrieved 2007/10/03.