2-(2,4-dimethoxyphenyl)-N-tosylpyrrolidine

Base Information

• Chemical Name: 2-(2,4-dimethoxyphenyl)-N-tosylpyrrolidine
• CAS No.: 949723-88-0
• Molecular Formula: C₁₉H₂₃NO₄S
• Molecular Weight: 361.462
• Mol file: 949723-88-0.mol

Synonyms:2-(2,4-dimethoxyphenyl)-N-tosylpyrrolidine

Chemical Property of 2-(2,4-dimethoxyphenyl)-N-tosylpyrrolidine

Chemical Property:

Purity/Quality:

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Technology Process of 2-(2,4-dimethoxyphenyl)-N-tosylpyrrolidine

There total 2 articles about 2-(2,4-dimethoxyphenyl)-N-tosylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

C14H18ClNO3S + 1,3-Dimethoxybenzene (151-10-0) → 2-(2,4-dimethoxyphenyl)-N-tosylpyrrolidine (949723-88-0) + anti-1-(2,4-dimethoxyphenyl)-2-(1-tosylpyrrolidin-2-yl)propan-1-one + 2,4-dimethoxypropiophenone (831-00-5)

Guidance literature:

With indium(III) triflate; In 1,2-dichloro-ethane; at 23 ℃; optical yield given as %de; Molecular sieve;

Reference yield:

C14H18ClNO3S + 1,3-Dimethoxybenzene (151-10-0) → 2-(2,4-dimethoxyphenyl)-N-tosylpyrrolidine (949723-88-0) + anti-1-(2,4-dimethoxyphenyl)-2-(1-tosylpyrrolidin-2-yl)propan-1-one + anti-1-(2,4-dimethoxyphenyl)-2-(1-tosylpyrrolidin-2-yl)propan-1-one + 2,4-dimethoxypropiophenone (831-00-5)

Guidance literature:

With indium(III) triflate; In 1,2-dichloro-ethane; at 23 ℃; optical yield given as %de; Molecular sieve;

upstream raw materials:

1,3-Dimethoxybenzene

Refernces