8-chloro-1-octanal

Base Information

• Chemical Name: 8-chloro-1-octanal
• CAS No.: 72359-96-7
• Molecular Formula: C₈H₁₅ClO
• Molecular Weight: 162.66
• Mol file: 72359-96-7.mol

Synonyms:8-chloro-1-octanal

Chemical Property of 8-chloro-1-octanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 8-chloro-1-octanal

There total 1 articles about 8-chloro-1-octanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclooctanol (696-71-9) → 9-oxa-bicyclo[4.2.1]nonane (284-20-8) + cycloactanone (502-49-8) + 8-chloro-1-octanal (72359-96-7)

Guidance literature:

With lead(IV) acetate; lithium chloride; In benzene; at 80 ℃; Yield given. Yields of byproduct given;

DOI:10.1007/BF00959880

Reference yield: 75.0%

8-chloro-1-octanal (72359-96-7) + benzoic acid (65-85-0,8013-63-6) → 8-chloro-1-oxooctan-2-yl benzoate (1312799-53-3)

Guidance literature:

With piperidine; tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In ethyl acetate; at 20 - 50 ℃; for 4h;

DOI:10.1002/anie.201101522

Reference yield:

8-chloro-1-octanal (72359-96-7) → (E)-10-hydroxy-dec-2-enoic acid (14113-05-4)

Guidance literature:

Multi-step reaction with 3 steps

1: Py, piperidine

2: NaI / acetone

3: (i) KOAc, AcOH, Py, (ii) KOH

With piperidine; pyridine; sodium iodide; In acetone;

upstream raw materials:

cyclooctanol

Downstream raw materials:

(E)-10-hydroxy-dec-2-enoic acid

8-chloro-1-oxooctan-2-yl benzoate

4-methyl-N-(9-methyldec-8-en-1-yl)benzenesulfonamide

N-(6,9-dihydroxy-9-methyldecyl)-4-methylbenzenesulfonamide

Refernces