1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate

Base Information

• Chemical Name: 1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate
• CAS No.: 1363906-80-2
• Molecular Formula: C₉H₁₅N₂O*C₂₄H₂₀B
• Molecular Weight: 486.465
• Mol file: 1363906-80-2.mol

Synonyms:1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate

Chemical Property of 1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate

There total 1 articles about 1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

DBN (3001-72-7) + sodium tetraphenyl borate (143-66-8) + acetyl chloride (75-36-5) → 1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate (1363906-80-2)

Guidance literature:

In acetonitrile; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jo202647f

Reference yield: 99.0%

1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate (1363906-80-2) + 1-amino-3-methylbenzene (108-44-1) → 3-Methylacetanilide (537-92-8)

Guidance literature:

In acetonitrile; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jo202647f

Reference yield: 99.0%

1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate (1363906-80-2) + benzylamine (100-46-9) → N-(phenylmethyl)acetamide (588-46-5)

Guidance literature:

In acetonitrile; at 80 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jo202647f

upstream raw materials:

DBN

sodium tetraphenyl borate

acetyl chloride

Downstream raw materials:

N-(acetyl)pyrrolidine

4-acetylmorpholine

N-acetylpiperidine

4-acetylaminopyridine

Refernces

• 1、 Taylor, James E.,Williams, Jonathan M.J.,Bull, Steven D.. "N-acyl 1,5-diazabicyclo[4.3.0]non-5-ene (DBN) tetraphenylborate salts as O-acylating agents". experimental part. p. 4074 - 4076. Retrieved 2012/08/28.