CONHC₄H₉C₂H₂C₆H₅CH₂

Base Information

• Chemical Name: CONHC₄H₉C₂H₂C₆H₅CH₂
• CAS No.: 99564-62-2
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.311
• Mol file: 99564-62-2.mol

Synonyms:CONHC₄H₉C₂H₂C₆H₅CH₂

Chemical Property of CONHC₄H₉C₂H₂C₆H₅CH₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of CONHC₄H₉C₂H₂C₆H₅CH₂

There total 2 articles about CONHC₄H₉C₂H₂C₆H₅CH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

N-tert-Butylacrylamide (107-58-4,25267-41-8) + potassium o-tolyltrifluoroborate → CONHC4H9C2H2C6H5CH2 (99564-62-2)

Guidance literature:

With triphenylphosphine; chlorobis(ethylene)rhodium dimer; In 1,4-dioxane; acetone; Heating;

DOI:10.1021/ol071098q

Reference yield: 74.0%

N-tert-Butylacrylamide (107-58-4,25267-41-8) + 2-methylchlorobenzene (95-49-8) → CONHC4H9C2H2C6H5CH2 (99564-62-2)

Guidance literature:

With potassium phosphate; Pd((CH₃)2C₆H₃NC(CH₃)CHC(CH₃)NC₆H₃(CH₃)2)(CH₃)(P(CH₂CH₃)3); tetrabutylammomium bromide; In water; N,N-dimethyl-formamide; at 85 ℃; for 12h; optical yield given as %de; stereoselective reaction;

DOI:10.1021/ol202177k

upstream raw materials:

N-tert-Butylacrylamide

2-methylchlorobenzene

Refernces

• 1、 Martinez, Remi,Voica, Florina,Genet, Jean-Pierre,Darses, Sylvain. "Base-free mizoroki-heck reaction catalyzed by rhodium complexes". . p. 3213 - 3216. Retrieved 2008/02/11.