Quinoline-7,8-diamine

Base Information

• Chemical Name: Quinoline-7,8-diamine
• CAS No.: 78105-42-7
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 159.191
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID30506126
• Nikkaji Number: J3.371.211A
• Wikidata: Q82361716
• Mol file: 78105-42-7.mol

Synonyms:Quinoline-7,8-diamine;78105-42-7;SCHEMBL9374479;DTXSID30506126;EN300-2504338

Chemical Property of Quinoline-7,8-diamine

Chemical Property:

• PSA: 64.93000
• LogP: 2.56160
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 159.079647300
• Heavy Atom Count: 12
• Complexity: 160

Purity/Quality:

99%, ^*data from raw suppliers

7,8-Quinolinediamine 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C(C=C2)N)N)N=C1

Technology Process of Quinoline-7,8-diamine

There total 15 articles about Quinoline-7,8-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

7-amino-8-nitroquinoline (42606-36-0) → 7,8-diaminoquinoline (78105-42-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/S0022-1139(00)82282-4

Reference yield: 61.0%

7,8-diaminoquinoline hydrochloride (1609035-46-2) → 7,8-diaminoquinoline (78105-42-7)

Guidance literature:

With sodium hydroxide; In water;

DOI:10.3762/bjoc.9.302

Reference yield: 31.0%

6-chloro[1,2,5]selenadiazolo[3,4-h]quinoline (1609035-44-0) → 7,8-diaminoquinoline (78105-42-7)

Guidance literature:

With acetic acid; zinc; for 4h; Reflux;

DOI:10.3762/bjoc.9.302

upstream raw materials:

7-amino-8-nitroquinoline

8-amino-7-nitroquinoline

7-chloro-8-nitroquinoline

7-nitroquinoline

Downstream raw materials:

imidazo<4,5-h>quinoline

Refernces

• 1、 Ashford, Dennis L.,Glasson, Christopher R. K.,Norris, Michael R.,Concepcion, Javier J.,Keinan, Shahar,Brennaman, M. Kyle,Templeton, Joseph L.,Meyer, Thomas J.. "Controlling ground and excited state properties through ligand changes in ruthenium polypyridyl complexes". . p. 5637 - 5646. Retrieved 2014/06/23.
• 2、 Sharma,Kumari,Singh. "Condensed heterocycles; XI. Synthesis of 1,2,5-thia(selena)diazolo[3,4-b]quinolines and 1,2,5-thia(selena)diazolo[3,4-h]quinolines". . p. 316 - 318. Retrieved 2007/10/02.