2-(2-Bromoethyl)pyridine hydrobromide

Base Information

• Chemical Name: 2-(2-Bromoethyl)pyridine hydrobromide
• CAS No.: 72996-65-7
• Molecular Formula: C7H9Br2N
• Molecular Weight: 266.963
• Hs Code.: 2933399090
• European Community (EC) Number: 676-388-6,812-074-9
• DSSTox Substance ID: DTXSID40512814
• Mol file: 72996-65-7.mol

Synonyms:2-(2-BROMOETHYL)PYRIDINE HYDROBROMIDE;72996-65-7;2-(2-Bromoethyl)pyridine HBr;2-(2-BROMO-ETHYL)-PYRIDINE HYDROBROMIDE;2-(2-bromoethyl)pyridine;hydrobromide;MFCD08274972;Pyridine, 2-(2-bromoethyl)-, hydrobromide;2-(2-Bromoethyl)pyridineHydrobromide;2-(2-Bromoethyl)pyridine hydrobromic acid;SCHEMBL507536;Pyridine, 2-(2-bromoethyl)-, hydrobromide (1:1);2-bromoethylpyridine hydrobromide;DTXSID40512814;SAXTXIDZMKZQMV-UHFFFAOYSA-N;2-(2-bromoethyl)pyridinium bromide;2-(bromoethyl)pyridine hydrobromide;XCA99665;AKOS015891991;CS-W003488;2-(2-bromoethyl)-pyridine hydrobromide;AC-34188;AS-36542;SY004999;AM20061469;FT-0660266;EN300-206161;A848484;2-(2-Bromoethyl)pyridine--hydrogen bromide (1/1)

Chemical Property of 2-(2-Bromoethyl)pyridine hydrobromide

Chemical Property:

• Vapor Pressure: 0.00929mmHg at 25°C
• Boiling Point: 258.6 °C at 760 mmHg
• Flash Point: 110.2 °C
• PSA: 12.89000
• LogP: 2.97710
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 266.90813
• Heavy Atom Count: 10
• Complexity: 75.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2-Bromoethyl)pyridinehydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)CCBr.Br

Technology Process of 2-(2-Bromoethyl)pyridine hydrobromide

There total 3 articles about 2-(2-Bromoethyl)pyridine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-(2-Hydroxyethyl)pyridine (103-74-2) → 2-(2-Bromoethyl)pyridine hydrobromide (72996-65-7)

Guidance literature:

With hydrogen bromide;

DOI:10.1055/s-1987-33430

Reference yield:

phenyl 2-(2-pyridyl)ethyl ether (261360-86-5) → 2-(2-Bromoethyl)pyridine hydrobromide (72996-65-7)

Guidance literature:

With hydrogen bromide; Heating;

DOI:10.1021/jm00389a022

Reference yield:

α-picoline (109-06-8) → 2-(2-Bromoethyl)pyridine hydrobromide (72996-65-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Na, NH₃ (liq.) / 1.) -78 deg C, 1 h, 2.) RT, overnight

2: 48percent HBr / Heating

With ammonia; hydrogen bromide; sodium;

DOI:10.1021/jm00389a022

upstream raw materials:

2-(2-Hydroxyethyl)pyridine

phenyl 2-(2-pyridyl)ethyl ether

α-picoline

Downstream raw materials:

2,3,4,9-tetrahydro-9-(phenylmethyl)-2-[2-(2-pyridinyl)ethyl]-1H-pyrido[3,4-b]indole

1-(4-Fluoro-phenyl)-4-[2-(2-pyridin-2-yl-ethyl)-1,2,3,4-tetrahydro-β-carbolin-9-yl]-butan-1-one

4-(4-chlorophenyl)-1-[3-[1,2,3,4-tetrahydro-2-[2-(2-pyridinyl)ethyl]9H pyrido[3,4-b]indole-9-yl]propyl]-4-piperidinol

9-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-2-(2-pyridin-2-yl-ethyl)-2,3,4,9-tetrahydro-1H-β-carboline

Refernces

• 1、 -. "Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions". Page/Page column 37. . Retrieved 2010/11/24.
• 2、 Abou-Gharbia,Patel,Moyer,Muth. "Psychotropic agents: Synthesis and antipsychotic activity of substituted β-carbolines". . p. 1100 - 1105. Retrieved 2007/10/02.