tetramethyl 3,7-dihydroxybicyclononadiene tetracarboxylate

Base Information

• Chemical Name: tetramethyl 3,7-dihydroxybicyclononadiene tetracarboxylate
• CAS No.: 77589-54-9
• Molecular Formula: C17H20 O10
• Molecular Weight: 384.34
• Hs Code.: 2918199090
• Mol file: 77589-54-9.mol

Synonyms:tetramethyl 3,7-dihydroxybicyclononadiene tetracarboxylate

Chemical Property of tetramethyl 3,7-dihydroxybicyclononadiene tetracarboxylate

Chemical Property:

• Vapor Pressure: 7.04E-13mmHg at 25°C
• Refractive Index: 1.563
• Boiling Point: 517.6°C at 760 mmHg
• Flash Point: 182.7°C
• PSA: 145.66000
• Density: 1.457g/cm³
• LogP: 0.18470

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tetramethyl 3,7-dihydroxybicyclononadiene tetracarboxylate

There total 4 articles about tetramethyl 3,7-dihydroxybicyclononadiene tetracarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

3-oxopentanedioic acid dimethyl ester (1830-54-2) + malonaldehyde sodium salt (24382-04-5) → tetramethyl 3,7-dihydroxybicyclo<3.3.1>nona-2,6-diene-2,4,6,8-tetracarboxylate (77589-54-9)

Guidance literature:

With sodium hydroxide; sodium dihydrogenphosphate; In methanol; for 72h;

DOI:10.1021/jo00219a027

Reference yield: 67.0%

Malondialdehyde (542-78-9) + 3-oxopentanedioic acid dimethyl ester (1830-54-2) → dimethyl 2-hydroxyisophthalate (36669-06-4) + (1R,4S,5R,8S)-3,7-Dihydroxy-bicyclo[3.3.1]nona-2,6-diene-2,4,6,8-tetracarboxylic acid tetramethyl ester (77589-54-9)

Guidance literature:

With sodium hydroxide; In methanol; at 25 ℃; pH: 7;

Reference yield:

3-oxopentanedioic acid dimethyl ester (1830-54-2) + malonaldehyde sodium salt (24382-04-5) → dimethyl 2-hydroxyisophthalate (36669-06-4) + tetramethyl 3,7-dihydroxybicyclo<3.3.1>nona-2,6-diene-2,4,6,8-tetracarboxylate (77589-54-9)

Guidance literature:

With sodium hydroxide; sodium dihydrogenphosphate; In methanol; Product distribution; Mechanism; var. pH values and reagent concentrations;

DOI:10.1021/jo00219a027

upstream raw materials:

Malondialdehyde

3-oxopentanedioic acid dimethyl ester

malonaldehyde sodium salt

Refernces

• 1、 Bertz, Steven H.,Dabbagh, Gary. "Synthese von Bicyclononan-Derivaten unter physiologischen Bedingungen". . p. 317 - 318. Retrieved 2007/10/02.