2-BROMO-1-(4-ISOBUTYL PHENYL)-1-PROPANONE

Base Information

• Chemical Name: 2-BROMO-1-(4-ISOBUTYL PHENYL)-1-PROPANONE
• CAS No.: 77565-38-9
• Molecular Formula: C13H17 Br O
• Molecular Weight: 269.181
• Mol file: 77565-38-9.mol

Synonyms:2-bromo-1-[4-(2-methylpropyl)phenyl]propan-1-one;

Chemical Property of 2-BROMO-1-(4-ISOBUTYL PHENYL)-1-PROPANONE

Chemical Property:

• PSA: 17.07000
• LogP: 3.95020

Purity/Quality:

99%min ^*data from raw suppliers

2-Bromo-4'-tert-butylpropiophenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-1-(4-ISOBUTYL PHENYL)-1-PROPANONE

There total 1 articles about 2-BROMO-1-(4-ISOBUTYL PHENYL)-1-PROPANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

p-tert-butylpropiophenone (71209-71-7) → 2-bromo-1-(4-tert-butylphenyl)propan-1-one (77565-38-9)

Guidance literature:

With bromine; In chloroform; at 10 - 20 ℃; for 2h;

DOI:10.1016/j.dyepig.2011.10.015

Reference yield:

2-bromo-1-(4-tert-butylphenyl)propan-1-one (77565-38-9) → 1-(4-tert-butylphenyl)-2-hydroxypropan-1-one (868744-20-1)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 12 h / Reflux

2: water; sodium hydroxide / 1 h / Reflux

With water; sodium hydroxide; In acetone;

DOI:10.1016/j.dyepig.2011.10.015

Reference yield:

2-bromo-1-(4-tert-butylphenyl)propan-1-one (77565-38-9) → 1-(4-tert-butyl-phenyl)-propane-1,2-dione

Guidance literature:

Multi-step reaction with 3 steps

1: acetone / 12 h / Reflux

2: water; sodium hydroxide / 1 h / Reflux

3: pyridine; copper(ll) sulfate pentahydrate / water / Reflux

With pyridine; copper(ll) sulfate pentahydrate; water; sodium hydroxide; In water; acetone;

DOI:10.1016/j.dyepig.2011.10.015

upstream raw materials:

p-tert-butylpropiophenone

Downstream raw materials:

C₁₅H₁₈F₃NO₂

1-(4-tert-butylphenyl)-2-hydroxypropan-1-one

3-bromo-1-(4-tert-butylphenyl)propane-1,2-dione

C₁₇H₁₅BrN₄

Refernces

• 1、 Jang, Chun Keun,Song, Cheol Jun,Jung, Sung Jae,Jaung, Jae Yun. "Topochemically photoreacted fluorescent dimers of 2,3-dicyanopyrazines". experimental part. p. 49 - 54. Retrieved 2012/03/26.