acide (N-phenyl acetamido)-3 propanoique

Base Information

• Chemical Name: acide (N-phenyl acetamido)-3 propanoique
• CAS No.: 99855-42-2
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.229
• Mol file: 99855-42-2.mol

Synonyms:acide (N-phenyl acetamido)-3 propanoique

Chemical Property of acide (N-phenyl acetamido)-3 propanoique

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acide (N-phenyl acetamido)-3 propanoique

There total 10 articles about acide (N-phenyl acetamido)-3 propanoique which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.4%

ethyl 3-(N-acetyl-N-phenylamino)propionate → acide (N-phenyl acetamido)-3 propanoique (99855-42-2)

Guidance literature:

With potassium hydroxide; In methanol; at 20 - 25 ℃; for 4h;

Reference yield:

aniline (62-53-3) → acide (N-phenyl acetamido)-3 propanoique (99855-42-2)

Guidance literature:

Multi-step reaction with 3 steps

3: H₂SO₄

With sulfuric acid;

Reference yield:

ethyl 3-phenylaminopropionate (62750-11-2) → acide (N-phenyl acetamido)-3 propanoique (99855-42-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 2 h / 20 °C / Cooling with ice

2: potassium hydroxide / methanol / 4 h / 20 - 25 °C

With triethylamine; potassium hydroxide; In methanol; dichloromethane;

upstream raw materials:

N-(3,3-dichloro-allyl)-acetanilide

methyl 3-(phenylamino)propanoate

acetyl chloride

N-phenyl-β-alanine

Downstream raw materials:

dimethyl subarate

N,N'-butanediyl-bis-acetanilide

6-(Acetyl-phenyl-amino)-hexanoic acid methyl ester

Refernces

• 1、 -. "With anti-HIV active 3 - amino propionic acid piperidine amide compound, synthetic method and use". . . Retrieved 2017/08/25.