4-Chloropteridine

Base Information

• Chemical Name: 4-Chloropteridine
• CAS No.: 72700-48-2
• Molecular Formula: C₆H₃ClN₄
• Molecular Weight: 166.57
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID10428074
• Wikidata: Q82240852
• Mol file: 72700-48-2.mol

Synonyms:4-chloropteridine;72700-48-2;4-CHLORO-PTERIDINE;SCHEMBL4573957;DTXSID10428074;RPTAZGNUCCXMMY-UHFFFAOYSA-N;AMY15883;MFCD08061287;AKOS005208434;CS-0331227;FT-0648698

Chemical Property of 4-Chloropteridine

Chemical Property:

• Vapor Pressure: 0.00164mmHg at 25°C
• Refractive Index: 1.688
• Boiling Point: 303.8 °C at 760 mmHg
• Flash Point: 166 °C
• PSA: 51.56000
• Density: 1.536 g/cm³
• LogP: 1.07320
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 166.0046238
• Heavy Atom Count: 11
• Complexity: 143

Purity/Quality:

98.5% ^*data from raw suppliers

4-Chloropteridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C2C(=N1)C(=NC=N2)Cl

Technology Process of 4-Chloropteridine

There total 2 articles about 4-Chloropteridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pteridin-4-ol (700-47-0) → 4-chloro-pteridine (72700-48-2)

Guidance literature:

With trichlorophosphate; at 0 - 100 ℃; for 6.16667h;

Reference yield:

6-chloro-4,5-diaminopyrimidine (4316-98-7) + Glyoxal (131543-46-9,107-22-2) → 4-chloro-pteridine (72700-48-2)

Guidance literature:

With water; pH 7;

Reference yield:

4-chloro-pteridine (72700-48-2) → 4-aminopteridine (6973-01-9)

Guidance literature:

With ammonia; In 1,4-dioxane; N,N-dimethyl-formamide; at 100 ℃; for 5h;

upstream raw materials:

6-chloro-4,5-diaminopyrimidine

Glyoxal

pteridin-4-ol

Downstream raw materials:

4-aminopteridine

Refernces