5-(Propoxymethyl)furan-2-carbaldehyde

Base Information

• Chemical Name: 5-(Propoxymethyl)furan-2-carbaldehyde
• CAS No.: 1917-66-4
• Molecular Formula: C₉H₁₂O₃
• Molecular Weight: 168.192
• DSSTox Substance ID: DTXSID501279530
• Mol file: 1917-66-4.mol

Synonyms:5-(propoxymethyl)furan-2-carbaldehyde;1917-66-4;2-Furancarboxaldehyde, 5-(propoxymethyl)-;SCHEMBL697080;DTXSID501279530;AKOS002664802;5-(Propoxymethyl)-2-furancarboxaldehyde;CS-0449156

Chemical Property of 5-(Propoxymethyl)furan-2-carbaldehyde

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 168.078644241
• Heavy Atom Count: 12
• Complexity: 136

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCOCC1=CC=C(O1)C=O

Technology Process of 5-(Propoxymethyl)furan-2-carbaldehyde

There total 5 articles about 5-(Propoxymethyl)furan-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

propan-1-ol (71-23-8) + D-Fructose (57-48-7,18875-34-8) → 5-(propoxymethyl)-2-furan carboxaldehyde (1917-66-4) + Dipropyl ether (111-43-3) + propyl methanoate (110-74-7) + n-propyl levulinate (645-67-0)

Guidance literature:

With poly(p-styrenesulfonic acid)-grafted carbon nanotubes; at 120 ℃; for 24h; chemoselective reaction; Sealed tube; Green chemistry;

DOI:10.1039/c3gc41139g

Reference yield: 14.0%

propan-1-ol (71-23-8) + fructopyranose (6347-01-9) → 5-(propoxymethyl)-2-furan carboxaldehyde (1917-66-4) + n-propyl levulinate (645-67-0)

Guidance literature:

With titanium(IV) oxide; at 150 ℃; for 1h; under 15001.5 Torr; Inert atmosphere; Green chemistry;

DOI:10.1039/c3gc40909k

Reference yield:

propan-1-ol (71-23-8) + Sucrose (57-50-1) → 5-(propoxymethyl)-2-furan carboxaldehyde (1917-66-4) + n-propyl levulinate (645-67-0)

Guidance literature:

With boron trifluoride-tetrahydrofuran complex; tin(IV) chloride; at 180 ℃; for 40h; Overall yield = 89 %;

upstream raw materials:

propan-1-ol

D-fructose

D-Fructose

fructopyranose

Refernces

• 1、 Kuo, Chung-Hao,Poyraz, Altug S.,Jin, Lei,Meng, Yongtao,Pahalagedara, Lakshitha,Chen, Sheng-Yu,Kriz, David A.,Guild, Curtis,Gudz, Anton,Suib, Steven L.. "Heterogeneous acidic TiO2 nanoparticles for efficient conversion of biomass derived carbohydrates". . p. 785 - 791. Retrieved 2014/02/14.
• 2、 Liu, Ruliang,Chen, Jinzhu,Huang, Xing,Chen, Limin,Ma, Longlong,Li, Xinjun. "Conversion of fructose into 5-hydroxymethylfurfural and alkyl levulinates catalyzed by sulfonic acid-functionalized carbon materials". supporting information. p. 2895 - 2903. Retrieved 2013/10/08.