S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride

Base Information

• Chemical Name: S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride
• CAS No.: 113511-38-9
• Molecular Formula: C₁₀H₁₃NOS₂*ClH
• Molecular Weight: 263.812
• Mol file: 113511-38-9.mol

Synonyms:S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride

Chemical Property of S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride

There total 3 articles about S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

S-benzyl-S’-(2-tert-butoxycarbonylamino)ethyldithiocarbonate → S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride (113511-38-9)

Guidance literature:

With hydrogenchloride; water; In 1,4-dioxane; ethyl acetate; at 20 ℃; for 48h;

DOI:10.1021/acsmedchemlett.0c00527

Reference yield:

phenylmethanethiol (100-53-8) → S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride (113511-38-9)

Guidance literature:

Multi-step reaction with 3 steps

1: dichloromethane / 0.5 h / 20 °C / Inert atmosphere

2: dichloromethane / 23 h / 20 °C / Inert atmosphere

3: hydrogenchloride; water / ethyl acetate; 1,4-dioxane / 48 h / 20 °C

With hydrogenchloride; water; In 1,4-dioxane; dichloromethane; ethyl acetate;

DOI:10.1021/acsmedchemlett.0c00527

Reference yield:

S-benzyl 1H-imidazole-1-carbothioate → S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride (113511-38-9)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 23 h / 20 °C / Inert atmosphere

2: hydrogenchloride; water / ethyl acetate; 1,4-dioxane / 48 h / 20 °C

With hydrogenchloride; water; In 1,4-dioxane; dichloromethane; ethyl acetate;

DOI:10.1021/acsmedchemlett.0c00527

upstream raw materials:

phenylmethanethiol

Downstream raw materials:

thiazolidine-2-one

Refernces