5-Thiazolamine, 4-methyl-

Base Information

• Chemical Name: 5-Thiazolamine, 4-methyl-
• CAS No.: 72632-65-6
• Molecular Formula: C4H6 N2 S
• Molecular Weight: 114.171
• Hs Code.: 2934100090
• Mol file: 72632-65-6.mol

Synonyms:5-Thiazolamine, 4-methyl-

Chemical Property of 5-Thiazolamine, 4-methyl-

Chemical Property:

• Melting Point: 91 °C(Solv: dichloromethane (75-09-2))
• Boiling Point: 232.5±20.0 °C(Predicted)
• PKA: 5.38±0.10(Predicted)
• PSA: 67.15000
• Density: 1.258±0.06 g/cm3(Predicted)
• LogP: 1.61490

Purity/Quality:

NLT 98% ^*data from raw suppliers

4-methylthiazol-5-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-methylthiazol-5-amine (cas# 72632-65-6) is a useful reagent in research for preparation method of 5-?aminothiazole non-?steroidal compounds as anti-?inflammatory agents.

Technology Process of 5-Thiazolamine, 4-methyl-

There total 3 articles about 5-Thiazolamine, 4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylmalononitrile (3696-36-4) → 4-methyl-5-aminothiazole (72632-65-6)

Guidance literature:

With hydrogen sulfide; triethylamine; In dichloromethane;

Reference yield:

C5H6N2O2S → 4-methyl-5-aminothiazole (72632-65-6)

Guidance literature:

With sulfuric acid; In water; at 20 ℃; for 0.666667h; pH=2; Reflux;

Reference yield:

C4H4N4S → 4-methyl-5-aminothiazole (72632-65-6)

Guidance literature:

C₄H₄N₄S; With sulfuric acid; In 1,4-dioxane; for 1h; Reflux;

With sodium hydroxide; In 1,4-dioxane; water; pH=9;

upstream raw materials:

2-methylmalononitrile

Refernces

• 1、 -. "PYRAZOLE DERIVATIVES AS MODULATORS OF CALCIUM RELEASE -ACTIVATED CALCIUM CHANNEL". Page/Page column 71. . Retrieved 2011/04/26.