2-methoxymethyl-1,4-benzenediamine malic acid

Base Information

• Chemical Name: 2-methoxymethyl-1,4-benzenediamine malic acid
• CAS No.: 1369378-23-3
• Molecular Formula: C₄H₆O₅*C₈H₁₂N₂O
• Molecular Weight: 286.285
• Mol file: 1369378-23-3.mol

Synonyms:2-methoxymethyl-1,4-benzenediamine malic acid

Chemical Property of 2-methoxymethyl-1,4-benzenediamine malic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxymethyl-1,4-benzenediamine malic acid

There total 5 articles about 2-methoxymethyl-1,4-benzenediamine malic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(methoxymethyl)-4-nitroaniline (337906-35-1) + malic acid (617-48-1,78644-42-5) → 2-methoxymethyl-1,4-benzenediamine malic acid (1369378-23-3)

Guidance literature:

2-(methoxymethyl)-4-nitroaniline; With hydrogen; palladium 10% on activated carbon; In ethanol; water;

malic acid; With sodium sulfite; In ethanol; water; for 0.5h;

Reference yield:

2-(methoxymethyl)-p-phenylenediamine (337906-36-2) + malic acid (617-48-1,78644-42-5) → 2-methoxymethyl-1,4-benzenediamine malic acid (1369378-23-3)

Guidance literature:

With sodium sulfite; In ethanol; water; for 1h; Inert atmosphere;

Reference yield:

1-chloro-2-(chloromethyl)benzene (611-19-8) → 2-methoxymethyl-1,4-benzenediamine malic acid (1369378-23-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: nitric acid; sulfuric acid / -5 - 0 °C

2.1: sodium methylate / 1 h / 20 - 30 °C / Reflux

3.1: ammonia / formamide / 6 h / 200 °C / 4897.52 Torr / Inert atmosphere

4.1: hydrogen / palladium 10% on activated carbon / ethanol; water

4.2: 0.5 h

With sulfuric acid; ammonia; hydrogen; nitric acid; sodium methylate; palladium 10% on activated carbon; In ethanol; water; formamide;

upstream raw materials:

1-chloro-2-(chloromethyl)benzene

2-(methoxymethyl)-4-nitroaniline

malic acid

1-chloro-2-(chloromethyl)-4-nitrobenzene

Refernces

• 1、 -. "METHODS OF SYNTHESIZING 2-METHOXYMETHYL-1,4-BENZENEDIAMINE". . . Retrieved 2012/04/17.