Technology Process of (S)-4-(4-(4-fluorophenyl)-5,5-dimethyl-2-oxooxazolidin-3-yl)-N-(quinolin-8-yl)benzamide
There total 6 articles about (S)-4-(4-(4-fluorophenyl)-5,5-dimethyl-2-oxooxazolidin-3-yl)-N-(quinolin-8-yl)benzamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium phosphate; copper(l) iodide; N,N`-dimethylethylenediamine;
In
1,4-dioxane;
at 140 ℃;
for 2h;
Inert atmosphere;
Sealed tube;
Microwave irradiation;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: thionyl chloride / 2 h / Reflux
2: diethyl ether / 0 - 20 °C
3: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1.5 h / 0 °C
4: potassium phosphate; N,N`-dimethylethylenediamine; copper(l) iodide / 1,4-dioxane / 2 h / 140 °C / Inert atmosphere; Sealed tube; Microwave irradiation
With
potassium phosphate; copper(l) iodide; thionyl chloride; N-ethyl-N,N-diisopropylamine; N,N`-dimethylethylenediamine;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diethyl ether / 0 - 20 °C
2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1.5 h / 0 °C
3: potassium phosphate; N,N`-dimethylethylenediamine; copper(l) iodide / 1,4-dioxane / 2 h / 140 °C / Inert atmosphere; Sealed tube; Microwave irradiation
With
potassium phosphate; copper(l) iodide; N-ethyl-N,N-diisopropylamine; N,N`-dimethylethylenediamine;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether;