(1R,2S)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL

Base Information

• Chemical Name: (1R,2S)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL
• CAS No.: 71653-81-1
• Molecular Formula: C₁₇H₂₁NO
• Molecular Weight: 255.36
• Mol file: 71653-81-1.mol

Synonyms:Benzeneethanol,b-[(1-methylethyl)amino]-a-phenyl-, (R*,S*)-;

Chemical Property of (1R,2S)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL

Chemical Property:

• Vapor Pressure: 2.17E-06mmHg at 25°C
• Refractive Index: 1.572
• Boiling Point: 378.1 °C at 760 mmHg
• Flash Point: 98.2 °C
• PSA: 32.26000
• Density: 1.061 g/cm³
• LogP: 3.85020

Purity/Quality:

98%min ^*data from raw suppliers

(1R,2S)-2-(ISO-PROPYLAMINO)-1,2-DIPHENYLETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1R,2S)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL

There total 3 articles about (1R,2S)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(N-isopropylamino)-2-phenylacetonitrile (54810-54-7) + benzaldehyde (100-52-7) → 2-(isopropylamino)-1,2-diphenylethanol (71653-81-1,71653-82-2,75136-50-4,75136-51-5,101581-90-2,142508-07-4) + 2-(isopropylamino)-1,2-diphenylethanol (71653-81-1,71653-82-2,75136-50-4,75136-51-5,101581-90-2,142508-07-4)

Guidance literature:

2-(N-isopropylamino)-2-phenylacetonitrile; With potassium hexamethylsilazane; In tetrahydrofuran; at -50 ℃; for 0.05h;

benzaldehyde; In tetrahydrofuran; at -50 - -20 ℃; for 1.66667h;

With borane tetrahydrofuran; In tetrahydrofuran; at 20 ℃; for 15h;

DOI:10.1002/ejoc.200701205

Reference yield:

2-(N-isopropylamino)-2-phenylacetonitrile (54810-54-7) + benzaldehyde (100-52-7) → 2-(isopropylamino)-1,2-diphenylethanol (71653-81-1,71653-82-2,75136-50-4,75136-51-5,101581-90-2,142508-07-4) + 2-(isopropylamino)-1,2-diphenylethanol (71653-81-1,71653-82-2,75136-50-4,75136-51-5,101581-90-2,142508-07-4)

Guidance literature:

2-(N-isopropylamino)-2-phenylacetonitrile; With potassium hexamethylsilazane; In tetrahydrofuran; at -50 ℃; for 0.05h;

benzaldehyde; In tetrahydrofuran; at -50 - -20 ℃; for 1.66667h;

With borane tetrahydrofuran; In tetrahydrofuran; at 20 ℃; for 15h;

DOI:10.1002/ejoc.200701205

Reference yield:

→ 2-(isopropylamino)-1,2-diphenylethanol (71653-81-1,71653-82-2,75136-50-4,75136-51-5,101581-90-2,142508-07-4)

Guidance literature:

With methanol; nickel; Hydrogenation;

DOI:10.1021/jo50017a017

upstream raw materials:

2-(N-isopropylamino)-2-phenylacetonitrile

benzaldehyde

Refernces