3-chlorophenylglyoxal

Base Information

• Chemical Name: 3-chlorophenylglyoxal
• CAS No.: 27700-54-5
• Molecular Formula: C₈H₅ClO₂
• Molecular Weight: 168.579
• Mol file: 27700-54-5.mol

Synonyms:3-chlorophenylglyoxal

Chemical Property of 3-chlorophenylglyoxal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 3-chlorophenylglyoxal

There total 3 articles about 3-chlorophenylglyoxal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3'-Chloroacetophenone (99-02-5) → 3-chlorophenylglyoxal (27700-54-5)

Guidance literature:

With tris(2,2'-bipyridyl)ruthenium dichloride; dioxane dibromide; sodium L-ascorbate; In acetonitrile; at 20 ℃; for 8h; Irradiation; Green chemistry;

DOI:10.1016/j.tetlet.2017.01.013

Reference yield: 36.5%

→ 3-chlorophenylglyoxal (27700-54-5) + 3-methylthio-5-(3'-chlorophenyl)-1,2,4-triazine (69466-60-0)

Guidance literature:

Reference yield:

→ 3-chlorophenylglyoxal (27700-54-5)

Guidance literature:

3-Chlor-acetophenon, SeO2/sd. wss. Eg. (Methode D);

upstream raw materials:

3'-Chloroacetophenone

Downstream raw materials:

5-(3-chloro-phenyl)-pyrazine-2,3-dicarbonitrile

Refernces

• 1、 Kayukov, Ya. S.,Mar’yasov, M. A.,Nasakin, O. E.. "Antiproliferative Activity of 2-Aroyland 2-Heteroyl-1,1,3,3-Tetracyanoprop-2-en-1-ides". . . Retrieved 2020/05/22.
• 2、 Yu, Qi-Wen,Wu, Lu-Ping,Kang, Tian-Chen,Xie, Jin,Sha, Feng,Wu, Xin-Yan. "Enantioselective Cyanosilylation of α,α-Dialkoxy Ketones by Using Phosphine-Thiourea Dual-Reagent Catalysis". supporting information. p. 3992 - 3996. Retrieved 2018/07/31.