3-Bromo-dithiobenzoic acid ethyl ester

Base Information

• Chemical Name: 3-Bromo-dithiobenzoic acid ethyl ester
• CAS No.: 160911-77-3
• Molecular Formula: C₉H₉BrS₂
• Molecular Weight: 261.206
• Mol file: 160911-77-3.mol

Synonyms:3-Bromo-dithiobenzoic acid ethyl ester

Chemical Property of 3-Bromo-dithiobenzoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Bromo-dithiobenzoic acid ethyl ester

There total 2 articles about 3-Bromo-dithiobenzoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

S-ethyl 3-bromothiobenzoate (66920-03-4) → 3-Bromo-dithiobenzoic acid ethyl ester (160911-77-3)

Guidance literature:

With Lawessons reagent; In toluene; Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2010.03.045

Reference yield:

m-bromobenzoic acid (585-76-2) → 3-Bromo-dithiobenzoic acid ethyl ester (160911-77-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) SO₂Cl

2: 6H₄P(S)S>2

With Lawessons reagent; sulfuryl dichloride;

DOI:10.1039/c39940002081

Reference yield: 75.0%

3-Bromo-dithiobenzoic acid ethyl ester (160911-77-3) → 3-bromo-1-trifluoromethylbenzene (401-78-5)

Guidance literature:

With bromine trifluoride; In trichlorofluoromethane; at 0 ℃; for 0.0333333h;

DOI:10.1016/j.tet.2010.03.045

upstream raw materials:

S-ethyl 3-bromothiobenzoate

m-bromobenzoic acid

Downstream raw materials:

1-Bromo-3-(ethylsulfanyl-difluoro-methyl)-benzene

3-bromo-1-trifluoromethylbenzene

1-Bromo-3-(chloro-difluoro-methyl)-benzene

Refernces

• 1、 Rozen, Shlomo,Mishani, Eyal. "A Novel Method for Converting Aromatic Acids into Trifluoromethyl Derivatives using BrF3". . p. 2081 - 2082. Retrieved 2007/10/02.