3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide

Base Information

• Chemical Name: 3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide
• CAS No.: 114963-98-3
• Molecular Formula: C₁₈H₂₄N₂OS
• Molecular Weight: 316.467
• Mol file: 114963-98-3.mol

Synonyms:3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide

Chemical Property of 3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide

There total 1 articles about 3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

phenyl isothiocyanate (103-72-0) + 2-methyl-1-morpholinocyclohexene (6127-98-6) → 3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide (114963-98-3)

Guidance literature:

In chloroform; for 2h; Heating;

Reference yield: 65.0%

ethylene dibromide (106-93-4) + 3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide (114963-98-3) → 4-{2-Methyl-6-[3-phenyl-thiazolidin-(2Z)-ylidene]-cyclohex-1-enyl}-morpholine

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In benzene; for 1h; Ambient temperature;

Reference yield:

3-methyl-2-morpholinocyclohexene-1-carbothionic acid anilide (114963-98-3) → 2-Methyl-6-[3-phenyl-thiazolidin-(2Z)-ylidene]-cyclohexanone

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / 50percent aq. NaOH / benzyltriethylammonium chloride / benzene / 1 h / Ambient temperature

2: 48 percent / conc. HCl / acetic acid

With hydrogenchloride; sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In acetic acid; benzene;

upstream raw materials:

phenyl isothiocyanate

2-methyl-1-morpholinocyclohexene

Refernces