2-O-allyl-1,3-benzylideneglycerol

Base Information

• Chemical Name: 2-O-allyl-1,3-benzylideneglycerol
• CAS No.: 6543-12-0
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.268
• Mol file: 6543-12-0.mol

Synonyms:2-O-allyl-1,3-benzylideneglycerol

Chemical Property of 2-O-allyl-1,3-benzylideneglycerol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-O-allyl-1,3-benzylideneglycerol

There total 2 articles about 2-O-allyl-1,3-benzylideneglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

allyl bromide (106-95-6) + 2-phenyl-[1,3]dioxan-5-ol (1708-40-3) → 2-O-allyl-1,3-benzylideneglycerol (6543-12-0)

Guidance literature:

With tetrabutylammomium bromide; sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1002/1099-0690(200103)2001:5<875::AID-EJOC875>3.0.CO;2-R

Reference yield:

benzaldehyde (100-52-7) → 2-O-allyl-1,3-benzylideneglycerol (6543-12-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / CSA / dimethylformamide / 1 h / 70 °C

2: 92 percent / tetra-n-butylammonium bromide; NaH / dimethylformamide / 2 h / 20 °C

With camphor-10-sulfonic acid; tetrabutylammomium bromide; sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1002/1099-0690(200103)2001:5<875::AID-EJOC875>3.0.CO;2-R

Reference yield: 82.0%

2-O-allyl-1,3-benzylideneglycerol (6543-12-0) → 2-O-allyl-1-O-benzylglycerol (166372-24-3)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; at 0 ℃; for 2.5h;

DOI:10.1002/1099-0690(200103)2001:5<875::AID-EJOC875>3.0.CO;2-R

upstream raw materials:

allyl bromide

2-phenyl-[1,3]dioxan-5-ol

benzaldehyde

Downstream raw materials:

2-O-allyl-1-O-benzylglycerol

Refernces