Technology Process of 2-ethyl-3-methoxy-2-methyl-3-phenylpropanal
There total 5 articles about 2-ethyl-3-methoxy-2-methyl-3-phenylpropanal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
benzaldehyde dimethyl acetal;
With
scandium tris(trifluoromethanesulfonate);
In
dichloromethane;
at 20 ℃;
for 0.5h;
Inert atmosphere;
Molecular sieve;
(E)-dimethyl((2-methylbut-1-en-1-yl)oxy)(phenyl)silane;
In
dichloromethane;
at -78 ℃;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1002/anie.202101634
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 77 percent / m-chloroperbenzoic acid / CH2Cl2 / 1 h / 0 °C
2: 1.) BF3*OEt2, 2.) TiCl4 / 1.) CH2Cl2, -78 deg C, 5 min, 2.) -78 deg C, 40 min
With
boron trifluoride diethyl etherate; titanium tetrachloride; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 89 percent / m-chloroperbenzoic acid / CH2Cl2 / 1 h / 0 °C
2: 1.) BF3*OEt2, 2.) TiCl4 / 1.) CH2Cl2, -78 deg C, 5 min, 2.) -78 deg C, 40 min
With
boron trifluoride diethyl etherate; titanium tetrachloride; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
