Benzoicacid, 3-(4-methylphenoxy)-, methyl ester

Base Information

• Chemical Name: Benzoicacid, 3-(4-methylphenoxy)-, methyl ester
• CAS No.: 78303-09-0
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 242.274
• Mol file: 78303-09-0.mol

Synonyms:Methyl 3-(4-methylphenoxy)benzoate;Methyl 3-(p-tolyloxy)benzoate;

Chemical Property of Benzoicacid, 3-(4-methylphenoxy)-, methyl ester

Chemical Property:

• Boiling Point: 348.45 °C at 760 mmHg
• Flash Point: 144.78 °C
• Density: 1.131 g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoicacid, 3-(4-methylphenoxy)-, methyl ester

There total 4 articles about Benzoicacid, 3-(4-methylphenoxy)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

→ 3-p-tolyloxy-benzoic acid methyl ester (78303-09-0)

Guidance literature:

With dicyclohexyl-(3-(cyclohexyloxy)-2’,4’,6’-triisopropyl-6-methyl-[1,1’-biphenyl]-2-yl)phosphine; palladium(II) acetylacetonate; In 1,4-dioxane; at 160 ℃; for 24h; Inert atmosphere;

Reference yield:

p-cresol (106-44-5) → 3-p-tolyloxy-benzoic acid methyl ester (78303-09-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / K₂CO₃, Py, Cu, CuI / H₂O / 2 h / Heating

2: H₂SO₄

With pyridine; copper(l) iodide; sulfuric acid; copper; potassium carbonate; In water;

Reference yield:

3-chlorobenzoate (535-80-8) → 3-p-tolyloxy-benzoic acid methyl ester (78303-09-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / K₂CO₃, Py, Cu, CuI / H₂O / 2 h / Heating

2: H₂SO₄

With pyridine; copper(l) iodide; sulfuric acid; copper; potassium carbonate; In water;

upstream raw materials:

methanol

3-(p-tolyloxy)benzoic acid

p-cresol

3-chlorobenzoate

Downstream raw materials:

3-p-tolyloxy-benzoic acid (2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazide

3-p-tolyloxy-benzoic acid hydrazide

Refernces

• 1、 Nagarapu, Lingaiah,Ravirala, Narender,Akkewar, Dattatray M.. "Synthesis of some novel 1-aminomethyl-3-benzoylhydrazono-2-indolinones as potential antiinflammatory agents". . p. 1254 - 1257. Retrieved 2007/10/03.