2-(4-Bromophenyl)sulfonylethanol

Base Information

• Chemical Name: 2-(4-Bromophenyl)sulfonylethanol
• CAS No.: 107737-89-3
• Molecular Formula: C₈H₉BrO₃S
• Molecular Weight: 265.128
• European Community (EC) Number: 859-637-5
• ChEMBL ID: CHEMBL4575059
• Mol file: 107737-89-3.mol

Synonyms:2-(4-Bromophenyl)sulfonylethanol;107737-89-3;2-[(4-bromobenzene)sulfonyl]ethan-1-ol;2-((4-bromophenyl)sulfonyl)ethanol;2-[(4-bromophenyl)sulfonyl]ethanol;2-(4-bromobenzenesulfonyl)ethan-1-ol;SCHEMBL1938871;CHEMBL4575059;2-(4-bromophenylsulfonyl)ethanol;JEYIKZQANLPVBY-UHFFFAOYSA-N;MFCD00622691;AKOS009590940;BS-46433;CS-0157419;EN300-75417;F52982;Z431953074

Chemical Property of 2-(4-Bromophenyl)sulfonylethanol

Chemical Property:

• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 263.94558
• Heavy Atom Count: 13
• Complexity: 237

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1S(=O)(=O)CCO)Br

Technology Process of 2-(4-Bromophenyl)sulfonylethanol

There total 5 articles about 2-(4-Bromophenyl)sulfonylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-(2-hydroxyethylthio)bromobenzene (14703-92-5) → 4-(2-hydroxyethylsulfonyl)bromobenzene (107737-89-3)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; boric acid; In methanol; water; acetonitrile; at 55 ℃; for 4.36667h; Product distribution / selectivity;

Reference yield:

para-bromobenzenethiol (106-53-6) → 4-(2-hydroxyethylsulfonyl)bromobenzene (107737-89-3)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol / 2 h / Heating

2: 83.5 percent / hydrogen peroxide (30percent) / Na₂WO₄*2H₂O / ethanol; H₂O / 1 h / Heating

With potassium hydroxide; dihydrogen peroxide; sodium tungstate; In ethanol; water;

Reference yield:

4-(2-hydroxyethylthio)bromobenzene (14703-92-5) → 2-((4-bromophenyl)sulfinyl)ethanol + 4-(2-hydroxyethylsulfonyl)bromobenzene (107737-89-3)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In methanol; water; at 55 ℃;

DOI:10.1021/op800292b

upstream raw materials:

1,2-bis-(4-bromo-benzenesulfonyl)-ethane

4-(2-hydroxyethylthio)bromobenzene

para-bromobenzenethiol

Downstream raw materials:

4-(2-hydroxyethylsulfonyl)styrene

C₈H₇BrO₃S

1-bromo-4-(vinylsulfonyl)benzene

2-({4-[2-(1-benzoylpiperidin-4-yl)-4H-1,3-benzodioxin-6-yl]phenyl}sulfonyl)ethanol

Refernces

• 1、 -. "NEW COMPOUND". Paragraph 0316; 0340. . Retrieved 2019/11/26.
• 2、 -. "INDOLE DERIVATIVES AND USES THEREOF". Paragraph 00653; 00656; 00657. . Retrieved 2019/02/13.