EXO-N-HYDROXY-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXIMIDE

Base Information

• Chemical Name: EXO-N-HYDROXY-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXIMIDE
• CAS No.: 5596-17-8
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.148
• Hs Code.: 2925190090
• Mol file: 5596-17-8.mol

Synonyms:7-Oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboximide,N-hydroxy- (7CI,8CI);N-Hydroxy-1,4-epoxy-5-cyclohexene-2,3-dicarboximide;N-Hydroxy-3,6-epoxy-1,2,3,6-tetrahydrophthalimide;(3aR,4S,7R,7aS)-2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione;Exo-N-hydroxy-7-oxabicyclo(2.2.1)hept-5-ene-2,3-D;

Chemical Property of EXO-N-HYDROXY-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXIMIDE

Chemical Property:

• Vapor Pressure: 1.66E-07mmHg at 25°C
• Melting Point: 194 °C (dec.)(lit.)
• Refractive Index: 1.68
• Boiling Point: 384.8 °C at 760 mmHg
• PKA: 8.60±0.20(Predicted)
• Flash Point: 186.5 °C
• PSA: 66.84000
• Density: 1.728 g/cm³
• LogP: -0.74810
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

exo-N-Hydroxy-7-oxabicyclo-[2.2.1]hept-5-ene-2,3-dicarboximide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of EXO-N-HYDROXY-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXIMIDE

There total 2 articles about EXO-N-HYDROXY-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXIMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

furan (110-00-9) + maleic anhydride (108-31-6) → N-hydroxy-3,6-endoxo-1,2,3,6-tetrahydrophthalimide (5596-17-8,55029-20-4,146985-80-0)

Guidance literature:

Multistep reaction; (i) benzene, (ii) NH₂OH, MeOH;

DOI:10.1246/bcsj.44.1084

Reference yield:

→ exo‐N‐hydroxy‐7‐oxabicyclo[2.2.1]hept‐5‐ene‐2,3‐dicarboximide (5596-17-8,146985-80-0)

Guidance literature:

1,4-Epoxycyclohex-5-en-2,3-dicarboxylic anhydrid, NH2OH*HCl, aq. NaOH;

Reference yield: 87.0%

4-methacryloyloxybenzoic acid (15721-10-5) + N-hydroxy-3,6-endoxo-1,2,3,6-tetrahydrophthalimide (5596-17-8,55029-20-4,146985-80-0) → N-p-methacryloxybenzoyloxy-3,6-endoxo-1,2,3,6-tetrahydrophthalimide

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

upstream raw materials:

furan

maleic anhydride

Downstream raw materials:

2-acetoxy-3a,4,7,7a-tetrahydro-4,7-epioxido-isoindole-1,3-dione

2-benzoyloxy-3a,4,7,7a-tetrahydro-4,7-epioxido-isoindole-1,3-dione

2-phenoxycarbonyloxy-3a,4,7,7a-tetrahydro-4,7-epioxido-isoindole-1,3-dione

2-benzenesulfonyloxy-3a,4,7,7a-tetrahydro-4,7-epioxido-isoindole-1,3-dione

Refernces