L-Methionine beta-naphthylamide

Base Information

• Chemical Name: L-Methionine beta-naphthylamide
• CAS No.: 7424-16-0
• Molecular Formula: C₁₅H₁₈N₂OS
• Molecular Weight: 274.387
• European Community (EC) Number: 686-439-4
• DSSTox Substance ID: DTXSID00426488
• Nikkaji Number: J431.594D
• Wikidata: Q27162534
• Mol file: 7424-16-0.mol

Synonyms:7424-16-0;L-Methionine beta-naphthylamide;H-Met-Bna;H-Met-betaNA;(S)-2-Amino-4-(methylthio)-N-(naphthalen-2-yl)butanamide;(2S)-2-amino-4-methylsulfanyl-N-naphthalen-2-ylbutanamide;L-methionine 2-naphthylamide;AC1OCXNF;H-L-Met-betaNA;H-Met-NA;l-methionyl-2-naphthylamine;SCHEMBL10945123;CHEBI:90422;DTXSID00426488;N-(2-Naphthyl)-L-methioninamide;N-naphthalen-2-yl-L-methioninamide;MFCD00190955;H-Met-beta-naphthylamide, AldrichCPR;AKOS010400941;AS-46954;CS-0363190;F11020;Q27162534;Butanamide,2-amino-4-(methylthio)-N-2-naphthalenyl-,(2S)-

Chemical Property of L-Methionine beta-naphthylamide

Chemical Property:

• PSA: 80.42000
• LogP: 3.63200
• Storage Temp.: Store at 0°C
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 274.11398438
• Heavy Atom Count: 19
• Complexity: 298

Purity/Quality:

98%Min ^*data from raw suppliers

(S)-2-Amino-4-(methylthio)-N-(naphthalen-2-yl)butanamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CSCCC(C(=O)NC1=CC2=CC=CC=C2C=C1)N
• Isomeric SMILES: CSCC[C@@H](C(=O)NC1=CC2=CC=CC=C2C=C1)N

Technology Process of L-Methionine beta-naphthylamide

There total 2 articles about L-Methionine beta-naphthylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methionine-[2]naphthylamide (98575-79-2) → C15H18N2OS (85827-87-8) + Met-βNA (7424-16-0)

Guidance literature:

With chiral stationary phase including isopropyl-functionalized CF₆; In ethanol; n-heptane; trifluoroacetic acid; at 20 ℃; Purification / work up; Resolution of racemate;

Reference yield:

N-Phthalyl-L-methionin- (100734-74-5) → Met-βNA (7424-16-0)

Guidance literature:

With hydrazine hydrate; In ethanol;

Reference yield:

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + Met-βNA (7424-16-0) → tert.-butoxycarbonyl-L-phenylalanyl-L-methionine-β-naphthylamine + L-phenylalanyl-L-methionine-β-naphthylamide formate (85770-51-0)

Guidance literature:

In formic acid;

upstream raw materials:

N-Phthalyl-L-methionin-

methionine-[2]naphthylamide

Downstream raw materials:

L-phenylalanyl-L-methionine-β-naphthylamide formate

Refernces