SATP

Base Information

• Chemical Name: SATP
• CAS No.: 84271-78-3
• Molecular Formula: C9H11 N O5 S
• Molecular Weight: 245.256
• Hs Code.: 2933990090
• Mol file: 84271-78-3.mol

Synonyms:Ethanethioicacid, S-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl] ester (9CI);N-Succinimidyl S-acetylthiopropionate; SATP; SPTA

Chemical Property of SATP

Chemical Property:

• Vapor Pressure: 1.49E-05mmHg at 25°C
• Melting Point: 48-50oC
• Boiling Point: 366.1oC at 760 mmHg
• Flash Point: 175.2oC
• PSA: 106.05000
• Density: 1.4g/cm3
• LogP: 0.20130
• Storage Temp.: −20°C
• Solubility.: Chloroform, Ethyl Acetate

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Succinimidyl-S-acetylthiopropionate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-(Acetylthio)propionic acid N-succinimidyl ester may be used in oligosaccharide synthesis. It was used in binding antibody and ligand to atomic force microscope tips.

Technology Process of SATP

There total 1 articles about SATP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + 3-acetylsulfanyl-propionic acid (41345-70-4) → 3-acetylsulfanyl-propionic acid pyrrolidin-1-yl ester (84271-78-3)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 90.0%

D-(R)-phenylalanine (673-06-3,25191-15-5,658-69-5,67675-33-6) + 3-acetylsulfanyl-propionic acid pyrrolidin-1-yl ester (84271-78-3) → N-(3-Acetylthiopropionyl)-L-phenylalanine (97185-83-6)

Guidance literature:

With 4-methyl-morpholine; In water; N,N-dimethyl-formamide; for 4h; Ambient temperature;

Reference yield: 76.0%

γAbu-PS1 + 3-acetylsulfanyl-propionic acid pyrrolidin-1-yl ester (84271-78-3) → SATP-γAbu-PS1

Guidance literature:

In aq. phosphate buffer; dimethyl sulfoxide; for 0.666667h; pH=7.2;

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

3-acetylsulfanyl-propionic acid

Downstream raw materials:

N-(3-Acetylthiopropionyl)-L-phenylalanine

Refernces

• 1、 -. "HYDROGELS BASED ON FUNCTIONALIZED POLYSACCHARIDES". Page/Page column 27; 32. . Retrieved 2018/04/13.