2-Bromomethyl-3-hydroxypyridine hydrobromide

Base Information

• Chemical Name: 2-Bromomethyl-3-hydroxypyridine hydrobromide
• CAS No.: 87440-88-8
• Molecular Formula: C6H6 Br N O . Br H
• Molecular Weight: 268.936
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID20385169
• Mol file: 87440-88-8.mol

Synonyms:2-BROMOMETHYL-3-HYDROXYPYRIDINE HYDROBROMIDE;87440-88-8;2-(bromomethyl)pyridin-3-ol Hydrobromide;2-(bromomethyl)pyridin-3-ol;hydrobromide;SCHEMBL1329656;DTXSID20385169;YEZLFBCEZYSGQC-UHFFFAOYSA-N;MFCD00466476;AKOS015833575;2-(bromomethyl)-3-pyridinol hydrobromide;CS-0456624;FT-0611579;A842215;2-Bromomethyl-3-hydroxypyridine hydrobromide, AldrichCPR

Chemical Property of 2-Bromomethyl-3-hydroxypyridine hydrobromide

Chemical Property:

• Vapor Pressure: 1.45E-05mmHg at 25°C
• Melting Point: 191-193oC
• Boiling Point: 356.2oC at 760 mmHg
• Flash Point: 169.2oC
• PSA: 33.12000
• LogP: 2.64020
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 268.88739
• Heavy Atom Count: 10
• Complexity: 89.1

Purity/Quality:

99% ^*data from raw suppliers

2-Bromomethyl-3-hydroxypyridinehydrobromide 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 3699680
• Hazard Codes: Xn
• Statements: 34-41-37/38-22
• Safety Statements: 26-36/37/39-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(N=C1)CBr)O.Br

Technology Process of 2-Bromomethyl-3-hydroxypyridine hydrobromide

There total 2 articles about 2-Bromomethyl-3-hydroxypyridine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetoxy-2-acetoxymethyl-pyridine (67992-22-7) → 2-bromomethyl-3-hydroxypyridine hydrobromide (87440-88-8)

Guidance literature:

With water; hydrogen bromide;

DOI:10.1021/ja01177a006

Reference yield:

→ 2-bromomethyl-3-hydroxypyridine hydrobromide (87440-88-8)

Guidance literature:

With water; hydrogen bromide;

DOI:10.1039/jr9460001104

Reference yield:

2-bromomethyl-3-hydroxypyridine hydrobromide (87440-88-8) → 2-methyl-3-pyridinol (1121-25-1,55780-69-3)

Guidance literature:

With methanol; palladium on activated charcoal; Hydrogenation;

DOI:10.1021/ja01177a006

upstream raw materials:

3-acetoxy-2-acetoxymethyl-pyridine

Downstream raw materials:

2-methyl-3-pyridinol