4-(2,2-Dichlorocyclopropyl)phenyl acetate

Base Information

• Chemical Name: 4-(2,2-Dichlorocyclopropyl)phenyl acetate
• CAS No.: 144900-34-5
• Molecular Formula: C₁₁H₁₀Cl₂O₂
• Molecular Weight: 245.105
• Hs Code.: 2915390090
• European Community (EC) Number: 924-945-1
• DSSTox Substance ID: DTXSID00464441
• Nikkaji Number: J523.232E
• Mol file: 144900-34-5.mol

Synonyms:144900-34-5;4-(2,2-Dichlorocyclopropyl)phenyl acetate;4-(2,2-Dichlorocyclopropyl)phenol 1-acetate;[4-(2,2-dichlorocyclopropyl)phenyl] Acetate;Phenol, 4-(2,2-dichlorocyclopropyl)-, 1-acetate;Acetyl Ciprofibrate;4-(2,2-Dichlorocyclopropyl)phenylacetate;EC 924-945-1;4-(2,2-DICHLOROCYCLOPROPYL)PHENOL ACETATE;SCHEMBL6427362;DTXSID00464441;AMY40408;AKOS015909658;AC-25853;FT-0660574;NS00001363;4-(2, 2-Dichlorocyclopropyl) phenol 1-acetate;J-513254

Chemical Property of 4-(2,2-Dichlorocyclopropyl)phenyl acetate

Chemical Property:

• Appearance/Colour: white like or light brown crystalline powder
• Vapor Pressure: 0.12Pa at 25℃
• Boiling Point: 340.8±42.0 °C(Predicted)
• PSA: 26.30000
• Density: 1.35
• LogP: 3.27310
• Storage Temp.: 2-8°C
• Water Solubility.: 35.72mg/L at 25℃
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 244.0057849
• Heavy Atom Count: 15
• Complexity: 257

Purity/Quality:

99% ^*data from raw suppliers

4-(2,2-Dichlorocyclopropyl)phenylacetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1=CC=C(C=C1)C2CC2(Cl)Cl
• Uses: Acetyl Ciprofibrate is an intermediate of Ciprofibrate(C482475) which is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.

Technology Process of 4-(2,2-Dichlorocyclopropyl)phenyl acetate

There total 1 articles about 4-(2,2-Dichlorocyclopropyl)phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.1%

1-(4-acetylphenyl)-2,2-dichlorocyclopropane (40641-93-8) → 4-(2,2-dichlorocyclopropyl)phenyl acetate (144900-34-5)

Guidance literature:

With dihydrogen peroxide; acetic anhydride; acetic acid; iron(II) chloride; at 40 ℃; for 4h; Reagent/catalyst;

upstream raw materials:

1-(4-acetylphenyl)-2,2-dichlorocyclopropane

Refernces