Technology Process of 1-tert-butylamino-3-[4-[2-(1-pyrazolyl)ethoxy]phenoxy]-2-propanol
There total 5 articles about 1-tert-butylamino-3-[4-[2-(1-pyrazolyl)ethoxy]phenoxy]-2-propanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) sodium hydride / 1.) DMF, 5 min, 2.) DMF, 60 deg C, 30 min
2: 55 percent / H2 / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature
3: 1.) sodium hydride / 1.) DMF, 5 min, 2.) DMF, 60 deg C, 30 min
4: ethanol / 18 h / Ambient temperature
With
hydrogen; sodium hydride;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jm00370a012
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 55 percent / H2 / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature
2: 1.) sodium hydride / 1.) DMF, 5 min, 2.) DMF, 60 deg C, 30 min
3: ethanol / 18 h / Ambient temperature
With
hydrogen; sodium hydride;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jm00370a012
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) sodium hydride / 1.) DMF, 5 min, 2.) DMF, 60 deg C, 30 min
2: ethanol / 18 h / Ambient temperature
With
sodium hydride;
In
ethanol;
DOI:10.1021/jm00370a012