cytidine-5'-phosphodimorpholide

Base Information

• Chemical Name: cytidine-5'-phosphodimorpholide
• CAS No.: 122450-01-5
• Molecular Formula: C₁₇H₂₈N₅O₈P
• Molecular Weight: 461.412
• Mol file: 122450-01-5.mol

Synonyms:cytidine-5'-phosphodimorpholide

Chemical Property of cytidine-5'-phosphodimorpholide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of cytidine-5'-phosphodimorpholide

There total 2 articles about cytidine-5'-phosphodimorpholide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) + cytidine-5'-phosphodichloride (30784-94-2) → cytidine-5'-phosphodimorpholide (122450-01-5) + cytidine monophosphate (63-37-6,30811-80-4) + cytidine 5'-monophosphate morpholidate (76742-17-1)

Guidance literature:

With water; Yield given. Multistep reaction. Yields of byproduct given; 1.) triethyl phosphate, 5-7 deg C, 60 min, 2.) 5-7 deg C, 7 h;

DOI:10.1007/BF00764626

Reference yield:

cytidine-5'-phosphodichloride (30784-94-2) + choline phosphate calcium salt → citicoline (987-78-0) + cytidine-5'-phosphodimorpholide (122450-01-5) + cytidine monophosphate (63-37-6,30811-80-4) + cytidine 5'-monophosphate morpholidate (76742-17-1)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1007/BF00764626

upstream raw materials:

morpholine

cytidine-5'-phosphodichloride

Refernces