4-hydrazinylpyridine hydrochloride

Base Information

• Chemical Name: 4-hydrazinylpyridine hydrochloride
• CAS No.: 27256-91-3
• Molecular Formula: C5H7N3
• Molecular Weight: 109.131
• Hs Code.: 2933399990
• Mol file: 27256-91-3.mol

Synonyms:Pyridine,4-hydrazino- (6CI,7CI,8CI,9CI);4-Hydrazinopyridine;4-Pyridinylhydrazine;4-Pyridylhydrazine;

Chemical Property of 4-hydrazinylpyridine hydrochloride

Chemical Property:

• Vapor Pressure: 0.00265mmHg at 25°C
• Melting Point: 30 °C
• Refractive Index: 1.657
• Boiling Point: 286.4 °C at 760 mmHg
• PKA: 8.24±0.26(Predicted)
• Flash Point: 127 °C
• PSA: 50.94000
• Density: 1.222 g/cm³
• LogP: 1.14050

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Hydrazinylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Hydrazinylpyridine is Hydrazonopyrrolidine derivative for use in preventing and/or treating disorders associated to Acinetobacter baumannii.

Technology Process of 4-hydrazinylpyridine hydrochloride

There total 10 articles about 4-hydrazinylpyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-hydrazinopyridine hydrochloride (20815-52-5) → 4-pyridylhydrazine (27256-91-3)

Guidance literature:

With ion-exchange resin Ambersep 900-OH (Fluka); In methanol;

Reference yield: 89.0%

4-bromopyridine hydrobromide salt (74129-11-6) → 4-pyridylhydrazine (27256-91-3)

Guidance literature:

With hydrazine hydrate; for 2h; Reflux;

DOI:10.1002/ardp.201800247

Reference yield: 88.0%

4-chlorpyridine hydrochloride (7379-35-3) → 4-pyridylhydrazine (27256-91-3)

Guidance literature:

With hydrazine hydrate;

upstream raw materials:

4-Chloropyridine

4-(nitroamino)pyridine

hydrogenchloride

4-chlorpyridine hydrochloride

Downstream raw materials:

4-Chloropyridine

4-(2-(2-hydroxybenzylidene)hydrazinyl)pyridine

4-(2-(2-methylbenzylidene)hydrazinyl)pyridine

4-(2-(2-methoxybenzylidene)hydrazinyl)pyridine

Refernces

• 1、 Parlar, Sülünay,Erzurumlu, Yal??n,Ilhan, Recep,Ballar K?rm?z?bayrak, Petek,Alptüzün, Vildan,Erciyas, Ercin. "Synthesis and evaluation of pyridinium-hydrazone derivatives as potential antitumoral agents". . p. 1198 - 1205. Retrieved 2018/03/21.
• 2、 -. "ALKYNE-BRIDGED HETERO-AROMATICS AND USES THEREOF". Paragraph 0328; 0329. . Retrieved 2013/06/28.