Benzenecarboximidic acid, 2-amino- (9CI)

Base Information

• Chemical Name: Benzenecarboximidic acid, 2-amino- (9CI)
• CAS No.: 28144-70-9
• Molecular Formula: C7H8 N2 O
• Molecular Weight: 136.153
• Mol file: 28144-70-9.mol

Synonyms:Benzimidicacid, o-amino- (8CI); Anthranilimidic acid; Benzimidic acid, 2-amino-

Chemical Property of Benzenecarboximidic acid, 2-amino- (9CI)

Chemical Property:

• PSA: 70.10000
• LogP: 1.83310

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenecarboximidic acid, 2-amino- (9CI)

There total 64 articles about Benzenecarboximidic acid, 2-amino- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-nitrobenzamide (610-15-1) → anthranilic acid amide (28144-70-9,88-68-6)

Guidance literature:

With hydrogen; In 2-methyltetrahydrofuran; water; at 40 ℃; for 24h; under 15001.5 Torr; chemoselective reaction;

DOI:10.1039/c8cy01634h

Reference yield: 99.0%

anthranilic acid nitrile (1885-29-6) → anthranilic acid amide (28144-70-9,88-68-6)

Guidance literature:

With water; potassium carbonate; at 150 ℃; for 0.5h; Microwave irradiation;

DOI:10.1039/c2gc16637b

Reference yield: 96.0%

(2?aminophenyl)(1H?benzo[d][1,2,3]triazol?1?yl)methanone (117576-29-1) → anthranilic acid amide (28144-70-9,88-68-6)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 2h;

DOI:10.3998/ark.5550190.0013.818

upstream raw materials:

isatoic anhydride

1-acetyl-1H-indole-2,3-dione

2-nitrobenzamide

indole-2,3-dione

Downstream raw materials:

tryptanthrine

N-(2-carbamoylphenyl)phthalimide

ethyl (2-carbamoylphenyl)carbamate

N-(2-chloro-benzoyl)-anthranilic acid amide

Refernces

• 1、 Kijima, Masashi,Nambu, Yoko,Endo, Takeshi,Okawara, Makoto. "Selective Reduction of Monosubstituted Nitrobenzenes to Anilines by Dihydrolipoamide-Iron(II)". . p. 1434 - 1436. Retrieved 1984.
• 2、 Qian, Peng,Liu, Jiaojiao,Zhang, Yan,Wang, Zhiyong. "Tunable Electrosynthesis of Anthranilic Acid Derivatives via a C-C Bond Cleavage of Isatins". . p. 16008 - 16015. Retrieved 2021/07/31.
• 3、 -. "QUINAZOLINE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT OF CANCER". Paragraph 00165. . Retrieved 2021/08/13.