N-Fmoc-N-methyl-L-alanine benzhydyl ester

Base Information

• Chemical Name: N-Fmoc-N-methyl-L-alanine benzhydyl ester
• CAS No.: 1220527-64-9
• Molecular Formula: C₃₂H₂₉NO₄
• Molecular Weight: 491.587
• Mol file: 1220527-64-9.mol

Synonyms:N-Fmoc-N-methyl-L-alanine benzhydyl ester

Chemical Property of N-Fmoc-N-methyl-L-alanine benzhydyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Fmoc-N-methyl-L-alanine benzhydyl ester

There total 1 articles about N-Fmoc-N-methyl-L-alanine benzhydyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N-methyl-L-alanine benzhydryl ester (1220527-52-5) + (fluorenylmethoxy)carbonyl chloride (28920-43-6) → N-Fmoc-N-methyl-L-alanine benzhydyl ester (1220527-64-9)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃;

DOI:10.1007/s00726-008-0221-8

Reference yield: 96.0%

N-Fmoc-N-methyl-L-alanine benzhydyl ester (1220527-64-9) → N-(9-fluorenylmethoxycarbonyl)-N-methyl-L-alanine (84000-07-7)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; toluene; at 20 ℃; for 1h;

DOI:10.1007/s00726-008-0221-8

upstream raw materials:

N-methyl-L-alanine benzhydryl ester

(fluorenylmethoxy)carbonyl chloride

Downstream raw materials:

N-(9-fluorenylmethoxycarbonyl)-N-methyl-L-alanine

Refernces