6-TRIMETHYLSTANNANYLISOQUINOLINE

Base Information

• Chemical Name: 6-TRIMETHYLSTANNANYLISOQUINOLINE
• CAS No.: 552331-36-9
• Molecular Formula: C12H15NSn
• Molecular Weight: 291.96
• Hs Code.: 2933499090
• Mol file: 552331-36-9.mol

Synonyms:6-TRIMETHYLSTANNANYLISOQUINOLINE

Chemical Property of 6-TRIMETHYLSTANNANYLISOQUINOLINE

Chemical Property:

• PSA: 12.89000
• LogP: 2.78000

Purity/Quality:

98.5% ^*data from raw suppliers

6-(Trimethylstannyl)isoquinoline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-TRIMETHYLSTANNANYLISOQUINOLINE

There total 3 articles about 6-TRIMETHYLSTANNANYLISOQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

6-bromo-isoquinoline (34784-05-9) → 6-trimethylstannylisoquinoline (552331-36-9)

Guidance literature:

With hexamethyldistannane; Pd(PPh₃)4; In 2,4-dichlorophenoxyacetic acid dimethylamine;

Reference yield: 50.0%

6-bromo-isoquinoline (34784-05-9) + hexamethyldistannane (661-69-8) → 6-trimethylstannylisoquinoline (552331-36-9)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 2,4-dichlorophenoxyacetic acid dimethylamine; at 100 ℃; for 1h;

Reference yield:

6-bromo-3-chloro-isoquinoline (552331-06-3) → 6-trimethylstannylisoquinoline (552331-36-9) + 3-chloro-6-trimethylstannanyl-isoquinoline

Guidance literature:

upstream raw materials:

6-bromo-isoquinoline

hexamethyldistannane

6-bromo-3-chloro-isoquinoline

Refernces

• 1、 -. "Kinase inhibitors". Page/Page column 25. . Retrieved 2010/01/31.